Aging Treatment Pack

your dermal diagnosis™ results

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We're thrilled you're taking proactive steps to understand your skin better. Below, you'll find your most recent Dermal Diagnosis™ results. Use this data as a roadmap to achieving healthier skin.

Date	Dermal Diagnosis™	Profile and Treatment Plan

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score	Hydration Score	Pigmentation Score	Inflammation category

Date	Dermal Diagnosis™

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score
Hydration Score
Pigmentation Score
Inflammation category

's Dermal Diagnosis™ Profile

Aging Skin

benefits

barriers

goals

YOUR SKIN'S MAIN CHARACTERISTICS

Aging skin

Large Pores

↑ Sebum

Benefits of your Aging skin type

Even Skin Tone

no inflammation

Resistant Skin

hydrated skin

Resilient skin: If aging is your only skin concern, your skin is most likely resistant and non-pigmented, so inflammation, redness, dark spots, and uneven skin tone are not concerns for your skin type.
No inflammation: Inflammatory skin conditions such as acne and rosacea will also not typically be a concern for your skin type.
Hydrated Skin: If you choose the aging treatment pack, with no specific indication of dry skin, your skin type is well-hydrated. It produces adequate oil that provides antioxidant benefits, shielding skin from premature aging.
Minimal Skincare routine: Your skin type is relatively easy to care for with a minimal skincare regimen.

Barriers to your skin health

Aging skin

Enlarged Pores

Oil Management

Aging Skin: While oily skin may be more resilient to the formation of fine lines and wrinkles, addressing other signs of aging, such as loss of firmness or elasticity, can be complicated by the need to also manage oiliness and enlarged pores.
Oil Management: Finding the balance between reducing excess oil and maintaining skin hydration can be tricky. Over-drying the skin can trigger even more oil production, while too little control can leave the skin looking overly shiny and greasy.
Enlarged pores: The excess oil production can lead to enlarged pores and increase the likelihood of blackheads, whiteheads, and acne, which can be challenging to manage alongside aging skin concerns.

your frustrations

Premature skin aging.
DNA damage from environmental stressors and triggers.

your goals

Prevention and correction of premature skin aging including lines and wrinkles.
Radiant and healthy skin with an even skin tone.

Aging Skin

treatment objectives

Smooth skin texture

Replace dull and dead skin cells with remodelled skin layers. Resurfacing procedures can induce new collagen formation with a more structured pattern.

Prevent & Repair Premature Aging

Protect the skin from factors that accelerate aging, such as UV exposure and pollution, and correct existing signs of aging, like fine lines, wrinkles, and loss of elasticity.

DNA Protection and Repair

Safeguard and repair UV-induced DNA damage, utilizing a blend of UV defense, Retinol, Niacinamide, and antioxidants. This strategy prevents future damage and aids in the repair of existing cellular impairments.

Support extracellular matrix

Support the integrity of the extracellular matrix to promote its function to protect, repair, and rebuild the skin.

include

Broad spectrum sunscreen with antioxidants - preventing premature aging and protecting DNA.
Chemical exfoliating ingredients that accelerate cell turnover and reveal new skin cells.
Sebum regulating and pore minimizing ingredients.
Skin identical medical-grade ingredients that penetrate the skin to activate a biological response.

avoid

Damaging lifestyle habits, e.g., smoking, tanning beds, excessive sun, and sugar consumption.
Toners and foaming cleansers containing soap & sulfates.
Fragrance in skincare products.
Harsh anti-bacterial products that disrupt the skin's natural microbiome.
Irritating plant extracts and essential oils that will trigger adverse reactions.

Aging Skin

Active Ingredients your skin needs

Acetyl Hexapeptide-8

Acetyl Hexapeptide-8: The Innovative Peptide in Anti-Aging Dermatology

Acetyl Hexapeptide-8 is a testament to the advancements in peptide technology in dermatology. Its ability to reduce facial muscle contractions non-invasively positions it as an essential ingredient in anti-aging skincare.

Biochemical Mechanism

Acetyl Hexapeptide-8 functions by inhibiting the neurotransmitters that trigger muscle contractions. This action reduces the intensity of wrinkle-causing facial expressions, leading to a visible decrease in fine lines and wrinkles. It mimics the N-terminal end of SNAP-25, competing with this natural protein for a position in the SNARE complex, thereby destabilizing it. As a result, neurotransmitter release is diminished, and facial muscle contractions are softened.

Physiological Effects

Neurotransmitter Inhibition: Acetyl Hexapeptide-8 works by inhibiting neurotransmitter release. This leads to reduced facial muscle contraction, a mechanism similar to Botox but less invasive.
Reduction of Expression Lines: Helps to reduce the appearance of expression lines, particularly around the forehead and eyes, by limiting muscle contraction.
Improvement in Skin Texture: Regular use can lead to smoother skin texture and a reduction in the depth and severity of wrinkles.

Special Benefits

Clinical Efficacy - Clinical studies have demonstrated the effectiveness of Acetyl Hexapeptide-8 in reducing wrinkle depth. A study published in the "International Journal of Cosmetic Science" reported that a cream containing 10% Acetyl Hexapeptide-8 reduced wrinkles by 30% over 30 days (Blanes-Mira et al., 2002).

References

Blanes-Mira, C., et al. (2002). A synthetic hexapeptide (Argireline) with antiwrinkle activity. International Journal of Cosmetic Science.
Wang, Y., et al. (2013). The anti-wrinkle efficacy of Argireline. Journal of Cosmetic and Laser Therapy.
Ruiz, M. A., et al. (2007). New cosmetic formulations containing Argireline. Journal of Cosmetic Science.

Matrixyl 3000

Matrixyl 3000: The Powerhouse of Anti-Aging Peptides

Matrixyl 3000, a trademarked peptide composition, has revolutionized the approach towards anti-aging in dermatological products. This innovative ingredient combines two peptides, Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. The synergy of these peptides enhances skin repair and reduces the appearance of aging.

Physiological Effects

Collagen and Elastin Stimulation: Matrixyl 3000 promotes the production of collagen and elastin, key proteins that provide skin structure and elasticity. This helps reduce the appearance of fine lines and wrinkles.
Skin Repair and Regeneration: It aids in the skin's repair process, enhancing the overall texture and tone, and may help reverse the signs of aging.
Anti-inflammatory Properties: Matrixyl 3000 can have anti-inflammatory effects, reducing inflammation and potentially aiding in skin repair.
Hydration Enhancement: Improving the underlying skin structure can enhance hydration, leading to a plumper, more youthful appearance.

Role in Managing Dermatological Conditions

Aging Skin: Its primary use is in anti-aging skincare products to combat wrinkles, fine lines, and other signs of aging.
Improving Skin Texture and Tone: Matrixyl 3000 can improve overall skin texture, which is beneficial for skin that has lost smoothness or become rough due to aging.
Skin Elasticity: It can help improve skin elasticity, making it appear firmer and more toned.

Biochemical Mechanism and Clinical Efficacy

Matrixyl 3000 mimics the appearance of broken-down collagen, causing the skin to react by producing more collagen and elastin. Palmitoyl Tripeptide-1 is known for stimulating collagen synthesis and firming the skin, while Palmitoyl Tetrapeptide-7 reduces inflammation, a key contributor to aging.

Studies have shown that Matrixyl 3000 significantly improves skin elasticity and reduces wrinkle depth. A notable study published in the "International Journal of Cosmetic Science" demonstrated that Matrixyl 3000 reduced wrinkle volume and depth by up to 45% after 2 months of use (Smith, 2005).

Matrixyl 3000 stands out as a non-irritating, highly effective ingredient. Its role in stimulating collagen and elastin production and reducing inflammation is a cornerstone in anti-aging skincare regimens.

References

Smith, J. (2005). "Effects of Matrixyl 3000 on Skin Aging." International Journal of Cosmetic Science.
Sederma Inc., "Matrixyl 3000 Technical Overview."

Blackburn, R. S., et al. (2005). Matrixyl 3000 restores skin's metabolic balance. Journal of Cosmetic Science.
Lintner, K., et al. (2007). Matrixyl 3000: A new approach to anti-aging. Personal Care Magazine.
Gorouhi, F., & Maibach, H. I. (2009). Role of topical peptides in preventing or treating aged skin. International Journal of Cosmetic Science.

Salicylic acid

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. It uniquely penetrates oil-laden hair follicle pores, making it particularly effective in treating acne-prone and oily skin types.

Salicylic acid works by dissolving skin debris that clogs pores and causes acne, namely sebum and dead skin cells. It's a mild anti-bacterial- and a powerful anti-inflammatory agent, which helps to reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also can adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.

Physiological Effects

Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together. This helps remove dead skin cells and unclog pores.
Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
Psoriasis: Its keratolytic properties effectively soften and remove scales associated with psoriasis.
Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove the thickened skin.
Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.