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DermExcel™ | Litaderm Serum
DermExcel™ | Litaderm Serum
DermExcel™ | Litaderm Serum
DermExcel™ | Litaderm Serum
DermExcel™ | Litaderm Serum
DermExcel™

Litaderm serum: Trial

4.9 / 5.0 from 2320 reviews
Sale price$14.40 USD Regular price$16.00 USD

SIZE: 5ml

A scientifically formulated correction serum that targets various skin concerns, promoting a healthy and radiant complexion. Its powerful blend of multi-tasking active ingredients is supported by peer-reviewed medical literature, ensuring its effectiveness in improving and preventing hyperpigmentation, melasma, redness, acne, rosacea, premature aging, and pigmentation.

The key active ingredients in Litaderm Serum work synergistically to deliver remarkable benefits. Niacinamide, at 10% concentration, enhances skin appearance by reducing hyperpigmentation, promoting even skin tone, and combating inflammation related to acne and rosacea. At 1%, Bakuchiol provides targeted treatment for signs of aging and skin damage, supporting a youthful complexion. With a potent 10% concentration, Azelaic acid reduces hyperpigmentation, redness, and inflammation, contributing to overall healthier skin. Arbutin, comprising 4% of the formula, further aids in correcting hyperpigmentation and promoting a more even complexion.

With its carefully selected ingredients, Litaderm Serum offers a dynamic formulation that comprehensively addresses various skin concerns. Supported by scientific evidence, this serum effectively targets hyperpigmentation, melasma, redness, acne, rosacea, premature aging, and pigmentation. Regularly using Litaderm Serum improves skin tone, texture, and overall radiance, resulting in healthy, radiant, and even-toned skin. Experience the benefits of this targeted approach to achieve a revitalized and rejuvenated appearance.

DermExcel™ | Litaderm Serum
Litaderm serum: Trial Sale price$14.40 USD Regular price$16.00 USD

  • Aging Skin: Target early signs of aging, including fine lines and wrinkles, by promoting cell renewal and improving skin elasticity.
  • Hyperpigmentation: Specifically formulated to improve and prevent hyperpigmentation, helping to reduce the appearance of dark spots, uneven skin tone, and discoloration.
  • Melasma: Indicated for individuals who have developed patches of discoloration on their skin, particularly on the face, due to hormonal changes such as pregnancy or birth control use.
  • Redness and Inflammation: The active ingredients work synergistically to calm inflammation and reduce redness, promoting a more balanced and even-toned complexion.
  • Skin Damage: By boosting skin health and supporting skin regeneration, Litaderm Serum is indicated for individuals who have skin damage, possibly due to environmental factors like sun exposure.
  • Acne: Reduce inflammation associated with acne, regulate sebum production, and minimize the appearance of blemishes, contributing to clearer and healthier skin.
  • Rosacea: Reduce the visible signs of rosacea, including redness and enlarged blood vessels.
  • Dull Lifeless Skin: Reduces melanin production, leading to a more even skin tone.
  • Overall Skin Health: Nourishes and rejuvenates the skin, promoting a healthier and youthful complexion.

BENEFITS OF LITADERM SERUM

Targeted Acne Treatment: Effectively reduces acne breakouts by eliminating acne-causing bacteria and managing inflammation.

Sebum Regulation: Regulates excess sebum production, reducing complications and improving the appearance of oily skin.

Pigmentation Treatment: Litaderm Serum target hyperpigmentation through various pathways.

Anti-Inflammatory: Litaderm Serum reduces inflammation related to acne, rosacea, and premature aging due to its potent anti-inflammatory ingredients.

Skin Barrier Enhancement: Niacinamide in the serum enhances the skin's barrier function, protecting it from environmental stressors.

Anti-Aging: Promotes skin elasticity and reduces skin damage, helping to treat and prevent premature aging incl. fine lines and wrinkles.

Rosacea Treatment: Reduce redness and visible blood vessels in the face, and control microbial activity associated with Rosacea.

Anti-Microbial: Controls and Manage Microbial activity to promote a healthy skin microbiome.

ACTIVE INGREDIENTS IN LITADERM SERUM

INDICATIONS FOR LITADERM SERUM

  • Acne / Breakouts
  • Aging and sun-damaged skin
  • Dry and dehydrated skin
  • Dull and lifeless skin
  • Enlarged Pores
  • Pigmentation
  • Red and Inflamed skin
  • Rough skin texture
  • Shaving Bumps / Folliculitis

LITADERM ACTION ON ALL PIGMENTATION PHASES

MODE OF ACTION OF LITADERM SERUM ON PIGMENTATION

BLOCK ALPHA MELANOCYTE-STIMULATING Hormone

BAKUCHIOL

  • α-MSH is required for the development of pigmentation by binding to its specific receptor to upregulate the expression of tyrosinase.

Bakuchiol inhibits the pigmentation process by blocking melanocyte-stimulating hormone and tyrosinase activation.

Tyrosinase Inhibitor

AZELAIC ACID & ARBUTIN

  • Tyrosinase is the key enzyme in the first two steps of melanin production.
  • The inhibition of tyrosinase has an important role in preventing melanin accumulation in the skin.

Azelaic acid and Arbutin inhibit the pigmentation process by blocking tyrosinase catalytic activity and functionality.

Melanosome Transfer Inhibitor

NIACINAMIDE

  • Within a complex metabolic system, niacinamide controls the transcription of signalling molecules.

Niacinamide inhibits the transfer of melanin (pigment) to the skin cells and therefore inhibits the pigmentation process.

Destroy Damaged Melanocytes

AZELAIC ACID

  • Azelaic acid prevents abnormal melanocytes from multiplying by interfering with DNA synthesis and mitochondrial enzymes.
  • It only targets abnormally hyperactive melanocytes with no cytotoxic effect on normal, healthy-functioning melanocytes.

Azelaic prevents hyperpigmentation by inhibiting abnormal functioning melanocytes.

MODE OF ACTION OF LITADERM SERUM ON PIGMENTATION

α-Melanocyte Stimulating Hormone blocker

BAKUCHIOL

α-MSH is required for the development of pigmentation, by binding to its specific receptor to upregulate the expression of tyrosinase.

Bakuchiol blocks both the melanocyte-stimulating hormone and tyrosinase activation, and therefore inhibit the pigmentation process.

Tyrosinase Inhibitor

AZELAIC ACID & ARBUTIN

Tyrosinase is the key enzyme in the first two steps of melanin production. The inhibition of tyrosinase has an important role in order to prevent melanin accumulation in skin.

Azelaic acid and Arbutin inhibit the pigmentation process by blocking tyrosinase catalytic activity and functionality.

Melanosome Transfer Inhibitor

NIACINAMIDE

Within a complex metabolic system, niacinamide controls the transcription of signalling molecules.

Niacinamide inhibits the transfer of the pigment melanin to the skin cells, and therefore inhibits the pigmentation process. 

Destroy Damaged Melanocytes

AZELAIC ACID

Azelaic acid prevents abnormal melanocytes from multiplying by interfering with DNA synthesis and mitochondrial enzymes. It only targets abnormally hyperactive melanocytes with no cytotoxic effect on normal, healthy functioning melanocytes.

Azelaic prevents hyperpigmentation by inhibiting abnormal functioning melanocytes.

ROSACEA STAGES AND TREATMENT OBJECTIVES

A constant interplay exists among the skin, micro-organisms, and the environment to maintain a delicate balance. Disturbance of this balance negatively influences both the microflora and skin health.

In Rosacea, the micro-environment of the affected skin is substantially altered, resulting in a shift in the proportion or speciation of the resident microflora. Several micro-organisms have been shown to be increased or immuno-reactive in patients with rosacea.

Or skin contains pattern recognition receptors (PPR). These receptors detect harmful bacteria on our skin. When they detect these harmful bacteria, they bind to them and activate an immune response.

Receptors (PPR) don't activate the immune response for normal micro-flora on our skin. Rosacea-prone skin receptors (PPR) are hyper-reactive and/or have decreased tolerance. They have heightened sensitivity and trigger the inflammatory response of normal microbes, leading to the initial signs of rosacea.

NORMAL SKIN
PHASE 1

Healthy skin with a perfect balance between normal microflora and skin receptors.

The function of the receptors (PPR): Detect and bind harmful molecules and activate the immune response. These receptors should not trigger an immune response by binding to normal microflora.

PHASE 1

PPR (receptors) of Rosacea-prone skin bind to normal flora (they are not supposed to) and activate the immune response that causes inflammation.

PPR (receptors) of Rosacea-prone skin is hyper-reactive and sensitive. They can be activated by various environmental agents (fragrance, heat, spicy food, etc.)

PHASE 2
PHASE 3

This inflammatory environment leads to increased leucocyte and cathelicidin expression (anti-microbial peptide), causing certain normal microbes to be eliminated.

With normal flora out of the way, the opportunity arise for the overgrowth of other microbes to fill the space of the eliminated normal flora. The normal microbes' balance gets disturbed.

PHASE 3

Alterations in the micro-flora create a further imbalance that further elevates the inflammation process.

This leads to the worsening of the disease, and symptoms become more severe.

ROSACEA TREATMENT WITH LITADERM SERUM

AZELAIC ACID

Anti-inflammatory: Decrease the inflammation process leading to breakouts, redness and skin damage.

Anti-microbial: Bacteriostatic activity to both aerobic and anaerobic bacteria including P-acnes.

Antioxidant: Prevent DNA damage, and activation of inflammatory enzymes.

Anti-keratinizing: Inhibits skin cells (keratinocytes) from abnormally multiplying.

Sebum(oil) regulator: Inhibits sebum (oil) over-production, thus preventing bacterial growth and inflammation.

NIACINAMIDE

Anti-inflammatory: Reduce the inflammatory response by inhibiting inflammatory messengers.

Anti-microbial: Provides long-lasting protection against bacteria by activating an anti-microbial peptide response.

Sebum (oil) regulator: Reduce sebum (oil) production, thus preventing bacterial growth and inflammation.

Antioxidant: Prevent DNA damage and activation of inflammatory enzymes.

BAKUCHIOL

Anti-inflammatory: Suppresses pro-inflammatory cytokine expression. It is a potent anti-inflammatory agent able to control leukocytic functions.

Anti-bacterial: Significant antibacterial activities against Gram-positive and negative bacteria. 

Anti-keratinizing: Inhibits skin cells (keratinocytes) from abnormally multiplying.

Sebum (oil) regulator: Reduce sebaceous glands' activity, leading to less pore clogging and potentially less oil production.

REVIEWS FOR DERMEXCEL™ TREATMENT SERUMS

Customer Reviews

Based on 2320 reviews
95%
(2195)
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(86)
1%
(27)
0%
(4)
0%
(8)
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Best product ever. Just love it.

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Zelda Mey

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Liandri Dorfling
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LOVIT!!!

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Danae Marais
Amazing

Leaves my skin feeling light and not like I have a lot of product on. Would definitely recommend

K
Karin Cilliers

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123

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TREATMENT PACKS CONTAINING LITADERM SERUM

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FREQUENTLY ASKED QUESTIONS

DERMEXCEL™

Medical-grade skin care products formulated according to pharmaceutical standards of purity, potency, and stability. All active ingredients, and the concentrations and dosing protocols in which they are used are supported by data published in the peer-reviewed medical literature.

DermExcel™ takes an easy, effective and affordable approach to evaluating and treating the skin. Targeted treatments to improve skin conditions and maintain skin health.

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