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Firsthand™ treatment

Sale price$19.80 USD Regular price$22.00 USD

SIZE: 50ml

Rejuvenize, brighten and soothe dehydrated hands.

Firsthand™ stands as an advanced Physiological Ceramide-Dominant Barrier-Repair Therapy, constructed with a robust spectrum of moisturizing agents, constituting an intelligent moisturizing complex. The potency of this hand emulsion is amplified by its multifunctional formulation designed to promote collagen synthesis, attenuate the impact of solar damage, inhibit the reduction of skin elasticity, and mend a compromised skin barrier.

Key components such as Ceramides, Cholesterol, and Fatty acids work synergistically to reinforce the integrity of the skin's lipid barrier, bolstering its resilience against external insults. Incorporating Niacinamide invigorates cellular energy and ameliorates skin tone and texture, while d-panthenol, a potent vitamin B5 derivative, provides potent anti-inflammatory effects and aids in skin repair. Moreover, adding hyaluronic acid ensures optimum hydration by attracting and retaining moisture, which is vital for maintaining the skin's suppleness and health.

After utilizing Firsthand™, hands manifest signs of rejuvenation and radiance, while desiccation is thoroughly alleviated. The physiological enhancements rendered by Firsthand™ result in hands that appear and feel younger and stronger and exhibit enhanced health.


Dermaplan™ | Firsthand
Firsthand™ treatment Sale price$19.80 USD Regular price$22.00 USD

  • Aging hands: The inclusion of collagen-stimulating ingredients such as Niacinamide helps reduce the visible signs of aging, such as fine lines, wrinkles, and sun damage, making Firsthand beneficial for aging hands.
  • Dry Skin (Xerosis): Provides intense hydration to address the symptoms of dry skin, such as tightness, roughness, and flakiness.
  • Loss of elasticity: By promoting collagen synthesis and improving hydration, Firsthand helps enhance the elasticity and firmness of the hands, making it a suitable option for addressing loss of elasticity.
  • Sun-damaged hands: The collagen-boosting properties of Firsthand, coupled with its moisturizing agents, contribute to the reduction of sun-induced skin damage, promoting a more youthful and even skin tone.
  • Ichthyosis: Effective in addressing the scaling, roughness, and excessive dryness associated with ichthyosis, a genetic disorder that impairs the skin's ability to retain moisture.
  • Impaired barrier function: Firsthand's Physiological Ceramide-Dominant Barrier-Repair Therapy aids in repairing and strengthening the skin's natural barrier, which may be compromised due to environmental factors, harsh products, or excessive dryness.
  • Rough and textured hands: The combination of moisturizing agents, ceramides, and fatty acids in Firsthand works to improve the texture of the skin, providing a smoother and softer feel.
  • General hand care: Firsthand can be used as a part of a regular hand care routine to maintain optimal hydration, protect the skin barrier, and promote overall hand health.

INDICATIONS FOR FIRSTHAND™ TREATMENT

  • Aging and sun-damaged skin
  • Dermatitis / Eczema
  • Disrupted skin barrier
  • Dry and dehydrated skin
  • Itchiness (pruritus) / Ichthyosis
  • Red and Inflamed skin
  • Rough skin texture
  • Uneven skin tone with dark spots or patches

FIRSTHAND™ TREATMENT MODE OF ACTION

Deep Hydration

Medical glycerin, d-Panthenol, and Hyaluronic acid ensure that the skin is supplied with continuous moisture, thus reducing dryness and improving overall hydration.

Skin Barrier Repair

The combination of Ceramides, fatty acids, and Cholesterol in Hydrabase reinforces and restores the skin's natural barrier, helping it retain moisture and protecting it from external irritants.

Anti-aging

Niacinamide supports skin cell renewal and collagen synthesis, which helps reduce the appearance of fine lines, wrinkles, and other visible signs of aging, resulting in a revitalized and youthful complexion.

Improved skin texture and elasticity

By supplying the skin with essential nutrients and hydration, Hydrabase supports the improvement of skin texture and elasticity, making it appear smoother and more supple.

Sun-damaged Skin Repair

Hydrabase's nourishing ingredients help to replenish and rejuvenate sun-damaged skin, promoting the skin's natural healing process and reducing the impact of sun damage.

Soothing and Calming

The gentle formulation of Hydrabase is designed to provide soothing relief to sensitive and irritated skin, reducing inflammation and promoting skin comfort.

WHAT IS DRY SKIN?

  • Dry skin is characterised by the lack of moisture in the stratum corneum (SC). This is the outermost skin layer.
  • Water is the major softener of the skin, and when levels are low, cracks and fissures occur.
  • For the skin to appear and feel normal, the water content of the SC must be greater than 10%.
  • A disruption or defect in the skin's permeability barrier allows excessive water to be lost from within the skin into the atmosphere. Referred to as transepidermal water loss (TEWL).
  • When the skin becomes too dry, the outer skin layers stiffen and may develop cracks. The cracks become fissures in the skin that become irritated, inflamed, and itchy.

SKIN BARRIER FUNCTION

The 2 PRIMARY FUNCTIONS OF THE skin barrier

PERMEABILITY BARRIER

Creating a barrier against electrolytes- and moisture loss (TEWL - Trans-epidermal Water loss).

This function protects the skin against becoming dry.

ANTIMICROBIAL BARRIER

Creating a barrier against the entry of unwanted micro-organisms such as allergens and irritants. 

This function protects the skin against irritant dermatitis and skin infections.

PERMEABILITY BARRIER

Creating a barrier against electrolytes- and moisture loss
(TEWL - Trans-epidermal Water loss).

This function protects the skin against becoming dry.

ANTIMICROBIAL BARRIER

Creating a barrier against the entry of unwanted microorganisms such as allergens and irritants. 

This function protects the skin against irritant dermatitis and skin infections.

These barriers are localized in the epidermis's stratum corneum layer (the skin's outermost layer).

When these barrier functions are impaired, the result is - DRY SKIN

TREATMENT OBJECTIVES FOR DRY SKIN WITH BARRIER IMPAIRMENT

Physiological Barrier Repair with Lipid-based, Ceramide-dominant therapy.

Increase the moisture content of the epidermis.

Fill the gaps between skin cells and replace missing lipids.

Create a protective layer on top of the skin to prevent water loss and “seal” in moisture.

Increase cellular turnover by hydrating skin.

Relieve itching skin by increasing the skin's natural moisturising factor.

FIRSTHAND™ MOISTURISER CLASSES MODE OF ACTION

PHYSIOLOGIC LIPID-BASED BARRIER REPAIR

  • Barrier repair: Amplifies lipid production and replenishes the lamellar bilayers that are critical for normal barrier function and antimicrobial defense. It is quickly absorbed into the underlying nucleated cell layers, where they incorporate into lamellar bodies.
  • Accelerated healing: Promote skin healing and regeneration, particularly in damaged or compromised skin barriers.
  • Improved skin texture: Restore the skin's lipid balance, resulting in smoother, more supple skin and improved overall texture.
  • Enhanced skin resilience: By reinforcing the skin's natural barrier, the triple lipid therapy increases the skin's resilience against environmental stressors, irritants, and allergens, which can exacerbate dry skin conditions.
  • Reduced inflammation: Reduce inflammation associated with dry skin conditions like eczema or psoriasis, relieving redness and irritation.

Physiologically repair the lipid bilayers critical for normal barrier function and antimicrobial defence.

EMOLLIENTS

  • Skin barrier repair: Strengthen and restore the skin's lipid barrier, which is responsible for retaining moisture and protecting the skin from irritants, allergens, and harmful microorganisms.
  • Soothing: Soothe and calm irritated skin by reducing friction and providing a smooth, protective layer on the skin. This helps alleviate symptoms such as itching, redness, and inflammation.
  • Skin softening: Soften rough, dry, or scaly skin by providing hydration and promoting the natural shedding of dead skin cells. This leads to smoother, healthier-looking skin.
  • Improved skin texture: By hydrating and softening the skin, emollients can improve the overall appearance and texture of the skin, making it look and feel healthier and more radiant.

Fill the gaps between skin cells and replace missing lipids.

HUMECTANTS

  • Moisture retention: Humectants are hygroscopic, meaning they can absorb water from their surrounding environment. They draw moisture from the air and bind it to the skin, helping to keep the skin hydrated.
  • Enhanced penetration: Improve the absorption of other beneficial ingredients in the Curexema formulation, enabling these ingredients to penetrate deeper into the skin and provide their intended benefits more effectively.
  • Skin barrier support: By increasing the skin's hydration levels, humectants help support the skin's natural barrier function, which protects the skin from irritants, allergens, and harmful microorganisms.
  • Skin plumping: As humectants increase the skin's water content, they create a plumping effect, which reduces the appearance of fine lines and wrinkles and improves the overall texture and appearance of the skin.
  • Soothing: Soothe irritated or inflamed skin by providing hydration and reducing dryness, which may contribute to itching, redness, and discomfort.

The humectants in Firsthand attract and retain moisture within the skin, supporting its overall hydration and health.

OCCLUSIVES

  • Water loss prevention: Occlusives create a physical barrier on the skin's surface, preventing transepidermal water loss (TEWL). This helps to maintain hydration levels within the skin and prevent excessive dryness or dehydration.
  • Skin barrier support: By sealing in moisture and reducing water loss, occlusives help support and strengthen the skin's natural barrier function, which protects the skin from external irritants, allergens, and harmful microorganisms.
  • Healing promotion: Occlusives create a semi-occlusive barrier that provides an optimal environment for the skin to heal, particularly in cases of damaged or compromised skin barriers, as seen in conditions like eczema or dermatitis.
  • Protection from environmental factors: The barrier created by occlusives helps shield the skin from environmental factors like harsh weather conditions, pollution, and irritants that may contribute to skin dryness or irritation.

Occlusives in Firsthand create a protective layer on top of the skin that prevents water loss and “seals” in moisture.

FIRSTHAND™ BENEFITS BEYOND MOISTURISATION

REVIEWS ON DERMEXCEL™ MOISTURISERS

Customer Reviews

Based on 15 reviews
80%
(12)
20%
(3)
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(0)
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C
Charmaine Dettmer

Curexema

T
Telicia Annandale
Satisfied

Very satisfied with my product.

T
Telicia Annandale
Satisfied

Very satisfied with my product.

M
Mary Konopi
Firsthand treatment

Leaves my hands soft and well nourished.

M
Mary Konopi
Firsthand treatment

Leaves my hands soft and well nourished.

H
Helene Kotze
Firsthand treatment

Excellent product for hard working hands. Thick and creamy consistency that improves the look of aging and dry skin. Very easily absorbed with a most pleasant, natural scent.

DERMEXCEL™

Medical-grade skin care products formulated according to pharmaceutical standards of purity, potency, and stability. All active ingredients, and the concentrations and dosing protocols in which they are used are supported by data published in the peer-reviewed medical literature.

DermExcel™ takes an easy, effective and affordable approach to evaluating and treating the skin. Targeted treatments to improve skin conditions and maintain skin health.

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