Medi-Zinc Cleanser

Name: Medi-Zinc Cleanser
Brand: DermExcel™
SKU: DX-ZINC100
Price: 24.0 USD
Availability: InStock
Rating: 4.94 (758 reviews)

4.9 / 5.0 from 758 reviews

$24.00 USD

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A powerful hypoallergenic medicated solution with beneficial properties attributed to its active constituent, Zinc Pyrithione. This chemical compound, FDA-approved and clinically recognized, delivers strong antibacterial and antifungal action, making the cleanser an ideal choice for managing skin conditions associated with redness, flaking, irritation, and itching.

Zinc Pyrithione's efficacy, compounded by a gentle cleansing base, facilitates the lifting and removing of impurities, leaving the complexion refreshed. Concurrently, it sustains a tranquil skin environment, reducing inflammation and discomfort. As a daily cleansing aid, Medi-Zinc Cleanser proposes a reliable, scientifically-backed intervention in fostering skin health and comfort.

Zinc Pyrithione

Zinc pyrithione, a compound with potent antifungal and antibacterial properties, has established itself as a cornerstone in the treatment of various skin conditions, particularly those involving Malassezia yeast. Its effectiveness against seborrheic dermatitis and dandruff, which are often associated with an overgrowth of Malassezia species, makes it a key ingredient for many dermatological conditions.

Zinc pyrithione’s mode of action is multifaceted, primarily targeting the membrane of fungi and bacteria, thereby disrupting their growth and replication. One of its significant mechanisms involves inhibiting fungal cell membrane transport by blocking the energy production pathway, which is crucial for cell survival.

In Malassezia, yeast, a natural inhabitant of the skin flora, can overgrow and cause conditions like seborrheic dermatitis and dandruff; zinc pyrithione's antifungal action is particularly beneficial. It reduces the yeast population on the skin, thereby alleviating the symptoms associated with its overgrowth, such as flaking, irritation, and redness.

Its efficacy in treating seborrheic dermatitis is attributed to its ability to reduce the Malassezia count, diminish inflammatory responses, and soothe the skin. Similarly, in dandruff, which is often linked to an excess of Malassezia, zinc pyrithione effectively reduces flaking and itchiness, promoting a healthier scalp environment.

The efficacy of zinc pyrithione in the treatment of seborrheic dermatitis and dandruff is well-documented. Its safety profile and efficacy have been confirmed by numerous studies, with significant improvements observed in both scalp and skin conditions following regular use.

Physiological effects of Zinc Pyrithione

Antifungal Activity: It is effective against a range of fungi, including those that cause dandruff and seborrheic dermatitis. Zinc Pyrithione inhibits the division of fungal cells, reducing their proliferation.
Antibacterial Properties: This compound also exhibits antibacterial activity, making it useful in treating and preventing bacterial skin infections.
Anti-inflammatory Effects: Zinc Pyrithione can reduce inflammation, which is beneficial in alleviating symptoms of various inflammatory skin conditions.
Sebum Regulation: It helps in regulating sebum production, which can be beneficial for oily skin and conditions like acne.

Role in Managing Dermatologocal Conditions

Dandruff and Seborrheic Dermatitis: Zinc Pyrithione is a common ingredient in anti-dandruff shampoos and is effective in controlling the flaking and itching associated with these conditions.
Psoriasis: It can help manage the symptoms of psoriasis, particularly in reducing scaling and redness.
Acne: Due to its antibacterial and anti-inflammatory properties, Zinc Pyrithione can be beneficial in the treatment of acne.
Fungal Infections: It is effective in treating various fungal skin infections due to its antifungal properties.

References

Warshaw, E. M., et al. (2005). Efficacy of Zinc Pyrithione in Seborrheic Dermatitis and Dandruff. Dermatology.
Pierard-Franchimont, C., et al. (2002). Antidandruff shampoo efficacy in dandruff/seborrhoeic dermatitis. International Journal of Cosmetic Science.
Scheman, A., et al. (2000). Antimicrobial Activity of Zinc Pyrithione. American Journal of Infection Control.

REVIEWS

Customer Reviews

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USE DURING PREGNANCY

Medi-Zinc Cleanser is safe to use during pregnancy.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on:

Where We Ship From: Orders are dispatched from our facilities in USA and Australia, tailored to your shipping address for optimal efficiency.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in the USA and Australia will enjoy delivery within 1-4 business days. International orders will receive their orders from 6 to 25 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

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Our Secure Payment Promise backs every transaction with DermExcel. We partner with trusted payment providers to create the best shopping experience for you.

Simple. Effective. Ethical. That's not just our skincare philosophy but our approach to your security too.

Medi-Zinc Cleanser

$24.00 USD

Rosacea: The anti-inflammatory and antibacterial properties of Zinc Pyrithione help manage and alleviate the symptoms of rosacea.
Acne: The antibacterial properties of Zinc Pyrithione in Medi-Zinc Cleanser make it effective in managing acne by reducing bacteria on the skin's surface and controlling inflammation.
Seborrheic Dermatitis: This condition, which causes flaky, itchy, red skin, can be managed with the antifungal and anti-inflammatory properties of Zinc Pyrithione.
Redness: control and reduce redness associated with skin conditions like rosacea, dermatitis, and eczema.
Irritation: It is indicated for soothing skin irritation caused by various factors, including environmental aggressors, allergies, or sensitivities.
Itching: Medi-Zinc Cleanser provides relief from itching in itchy skin conditions such as contact dermatitis, insect bites, or allergic reactions.
Enlarged Pore Size: Helps minimize the appearance of enlarged pores.
Hyperpigmentation: Help to lighten areas of hyperpigmentation on the skin, leading to a more even skin tone.
Sensitive skin: Its hypoallergenic formulation makes it suitable for individuals with sensitive skin, providing a gentle and non-irritating cleansing option.
Psoriasis: The anti-inflammatory properties of Zinc Pyrithione can help manage the redness and irritation associated with psoriasis.
Eczema: While not a cure, the cleanser may help soothe the itching and inflammation associated with eczema.

Active ingredients

Zinc Pyrithione

Full ingredient list

Aqua, Polyethylene Glycol, Coco-Glucoside, Cocoamidopropyl Betaine, Sodium Lauroyl Sarcosinate, Zinc Pyrithione, Phenoxyethanol & Ethyl hexyl Glycerin, Acrylates Copolymer, Triethanolamine, Coco-Glucoside & Glyceryl Oleate

FACIAL AND BODY APPLICATION

Apply Medi-Zinc to the affected areas in the morning and/or evening unless otherwise suggested by your treating doctor or clinical advisor.
Slightly wet your fingers. If you apply Medi-Zinc to your face, ensure not to wet your face before applying, this will cause the product to run into your eyes and sting.
Keep the product in contact with your skin for at least 5 min. This will allow the product to penetrate the follicles optimally. Tip: Keep the cleanser on your skin while you brush your teeth/bath, or get dressed.
Remove the cleanser with a clean, lukewarm face cloth or the microfibre face sponge. This will also help to remove excess makeup and loose peeling skin.
Continue treatment once / twice daily until clearance of symptoms and then for at least one week after.
Because yeast, fungi, and bacteria do not develop resistance toward Zinc Pyrithione, you can continue to use Medi-Zinc cleanser regularly even after symptoms have cleared.
Consistent application of Zinc Pyrithione will result in continuous antimicrobial activity.

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IMPORTANT TIPS

Make sure the product has good contact with the skin. Lather the areas you would like to treat and keep the product on the skin for at least 5 min, but most preferably 10 min for best results. This will allow the product to penetrate the follicles to reach the Malassezia optimally.
Repeat the application nightly for at least 3-4 weeks. Within this timeframe, you will start to experience positive results as the Zinc Pyrithione controls the Malassezia overgrowth.
To keep the Malassezia yeast from returning, ensure you have enough Zinc Pyrithione hanging out in the skin around the problem areas. Do not stop your treatment after all the signs and symptoms have cleared up. Problem areas should be in contact with Zinc Pyrithione at least once per week.
The FDA has approved Zinc Pyrithione as very safe and effective. There is no harm in continuing to use the Zinc Pyrithione daily. Bacteria and the yeast on your skin will not become resistant to it, so there's no reason to stop using it.
Always remember the 5-10 min skin contact rule.

Medi-Zinc Cleanser

benefits

Antibacterial and Anti-fungal Action

Zinc Pyrithione is FDA-approved for effectively treating bacterial and fungal skin conditions.

Anti-Inflammatory

Medi-Zinc cleanser down-regulates the inflammatory response and therefore reduces redness, itching, and irritation.

Sebum Regulation

Regulates excess sebum production, reducing complications and improving the appearance of oily and enlarged pores.

Symptom Management

Control and reduce symptoms such as redness, flaking, irritation, and itching, thereby improving overall skin comfort.

Hypoallergenic

Suitable for individuals with sensitive skin, minimizing the risk of irritation or adverse reactions.

Promotes Healthy Skin

By addressing common skin concerns, Medi-Zinc Cleanser contributes to overall skin health.

Medi-Zinc Cleanser

INDICATIONS

Keratosis Pilaris

Shaving Bumps

Rosacea / Red Skin

Dermatitis / Eczema

Inflammation

Acne / Breakouts

Seborrheic Dermatitis

Tinea Versicolor

Medi-Zinc Cleanser

MODE OF ACTION

Anti-Inflammatory

Inflammation on the scalp contributes to itchiness, redness, and irritation, which are common symptoms of dandruff. Zinc pyrithione reduces inflammation on the scalp, which help to alleviate these symptoms.
Zinc Pyrithione positively affects the immune system by balancing pro-inflammatory and anti-inflammatory cytokines in the body. Studies published in the Journal of Dermatological Science indicate that Zinc Pyrithione increases the production of anti-inflammatory cytokines in human skin cells. These cytokines are known to be involved in the immune response and are important for regulating inflammation and promoting healing.
Studies further indicate that Zinc Pyrithione significantly reduces the pro-inflammatory cytokines interleukin-1 and tumor necrosis factor-alpha production. This action boosts the body's natural defenses against the yeast and reduces the severity of dandruff symptoms.
Cytokine production is a complex process that involves a delicate balance between pro-inflammatory and anti-inflammatory cytokines. Too much or too little cytokine production can lead to problems with inflammation and immune function. Zinc Pyrithione contributes to a healthy balance between inflammation and immune function.
Zinc pyrithione also has direct anti-inflammatory effects on the skin by reducing the production of certain enzymes that contribute to inflammation.

Anti-Fungal

Zinc Pyrithione has broad-spectrum antimicrobial activity: It inhibits and reduces the burden of Dandruff-causing Malassezia on the skin and targets gram-positive and gram-negative bacteria and other fungi that cause ringworm, athlete's foot, and jock itch.
Zinc Pyrithione disrupts iron distribution across the yeast wall and effectively starves the yeast of some of the critical processes important in its respiratory function.
Zinc Pyrithione disrupts the yeast's cell membrane, preventing it from proliferating and reproducing. Zinc pyrithione binds to the cell membrane of the yeast and causes damage to its structure, which ultimately leads to cell death.
Zinc pyrithione also interferes with the metabolic processes of the yeast. It disrupts the uptake of essential nutrients and alters the scalp's pH balance, making it more difficult for the yeast to survive and grow.
Zinc Pyrithione penetrates the hair follicle where Malassezia resides and has a unique slow-release ability. It persists in the top layer of skin even after rinsing off the product. Therefore, it imparts long-lasting control and sustained release of anti-yeast coverage and suppression of Malassezia yeast overgrowth.
The yeast, fungi, and bacteria do not develop resistance toward Zinc Pyrithione. Consistent application of Zinc Pyrithione will result in continuous antimicrobial activity.

Zinc Pyrithione

Zinc Pyrithione has broad-spectrum antimicrobial activity:
Not only does it inhibit and reduce the burden of Malassezia on the skin, but it also targets gram-positive and gram-negative bacteria, as well as other fungi that cause ringworm, athlete's foot, and jock itch.

Zinc Pyrithione disrupts iron distribution across the yeast wall and effectively starves the yeast of some of the critical processes important in its respiratory function.

Zinc Pyrithione penetrates the hair follicle where Malassezia resides and has a unique slow-release ability. It persists in the top layer of skin even after rinsing off the product. Therefore, it imparts long-lasting control and sustained release of anti-yeast coverage and suppression of the Malassezia yeast overgrowth.

The yeast, fungi, and bacteria do not develop resistance towards Zinc Pyrithione. Consistent application of Zinc Pyrithione will, therefore, result in continuous antimicrobial activity.

Cleansers

testimonials

Medi zinc cleanser

My teenage boys love their new skin. Thanx to medi zinc cleanser

Excellent Dermexcel products

I've been battling for years to find a skin product that assists with breakouts and inflammation. This product actually works and my skin has never looked better than now! So grateful!

Fantastic Cleanser

Mal oor die cleanser en xtra device van Dermexcel

Medi zinc

Love love love this product. Will definitely be ordering it again. Also inlove with the lipbalm I received. It keeps my lips moist throughout my days specially weekends in the sun when the boys are playing rugby. Just had an issue when O ordered. I ordered through pay just now. Orders above R500 is free delivery. You guys charhed me delivery fee which was not fair

Reduces appearance of pores

This cleanser has reduced shine on my T zone and minimizes pores which is great as one gets older.

Very Happy

My little 2 year old suffers from keratosis Polaris on his arms and legs, I found the cleanser and cream did start making a difference. It was only a tester size but I will definitely be getting a bigger size to continue the treatment. It was gentle enough not to burn him, but did make a difference to his skin. And I received a free lip treatment which was very thoughtful from the company.

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Medi-Zinc Cleanser

Physiological effects of Zinc Pyrithione

Role in Managing Dermatologocal Conditions

References

Customer Reviews