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Dermalytic

Sale priceR 305.00 ZAR

SIZE: 100 mL

A potent and clinically formulated ointment that effectively treats calloused, rough, and dry skin. It's more than a standard moisturizer; it exfoliates dead skin cells and replenishes moisture. The product creates an optimal environment for skin health, leading to a smoother complexion.

Key ingredients include 10% Glycolic acid for exfoliation, 10% Lactic acid for removing dead cells, and 20% Urea for lasting hydration. Its "cream-ointment" base balances efficacy and application comfort. Dermalytic's medical-grade formula and scientific skincare approach visibly improve skin texture, giving users a renewed sense of confidence and comfort.


Urea

Urea, a naturally occurring compound in the skin, is widely recognized in dermatology and skincare for its hydrating and keratolytic properties. It is a component of the skin's natural moisturizing factor (NMF) and plays a crucial role in maintaining skin hydration and barrier function.

In skincare, urea is valued for its dual action: it acts as a humectant, drawing moisture into the skin, and as a keratolytic agent, helping to break down the protein bonds between dead skin cells, leading to smoother and softer skin. This makes it particularly effective in treating dry, rough, and scaly skin conditions such as eczema, psoriasis, and ichthyosis.

Additionally, urea has been shown to have antimicrobial properties and can aid in skin barrier repair, further underscoring its utility in treating a variety of skin conditions.

Physiological Effects of Urea
  1. Hydration: Urea is a potent humectant, meaning it draws moisture into the skin, significantly improving hydration and maintaining skin moisture balance.
  2. Keratolytic Action: Urea has keratolytic properties, helping to break down the bonds between dead skin cells, aiding in the exfoliation of the skin's surface.
  3. Skin Barrier Function: Urea enhances the skin's barrier function, helping to prevent moisture loss and protect the skin from external irritants.
  4. Soothing Effect: It has a soothing effect on dry, itchy, and irritated skin, providing relief in various skin conditions.
Role in Managing Dermatological Skin Conditions
  1. Dry Skin (Xerosis): Urea is a key ingredient in many moisturizers for treating dry skin, due to its excellent hydrating properties.
  2. Eczema and Psoriasis: It helps manage symptoms like dryness, scaling, and itching in eczema and psoriasis.
  3. Ichthyosis and Keratosis Pilaris: The keratolytic action of urea makes it effective in conditions characterized by excessive skin scaling, such as ichthyosis and keratosis pilaris.
  4. Cracked Heels and Calluses: Urea-based creams are effective in softening and reducing thickened skin on heels and calluses.
  5. Aging Skin: It can improve skin texture and hydration in aging skin.
References
  • Lodén, M. (2003). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology.
  • Pan, M., et al. (2013). Efficacy of topical urea in the treatment of xerosis. American Journal of Clinical Dermatology.
  • Fluhr, J. W., et al. (2008). Glycerol and the skin: holistic approach to its origin and functions. British Journal of Dermatology.
  • Grether-Beck, S., Felsner, I., Brenden, H., Kohne, Z., Majora, M., Marini, A., ... & Krutmann, J. (2012). Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression. Journal of Investigative Dermatology, 132(6), 1561-1572.
Lactic acid

Lactic acid, a member of the alpha hydroxy acid (AHA) family, is a well-regarded ingredient in the field of dermatology and skincare for its exfoliating and moisturizing properties. Naturally occurring in sour milk and other fermented products, lactic acid is also produced in the human body and plays a role in various metabolic processes.

In skincare, lactic acid is primarily known for its ability to gently exfoliate the skin. By breaking down the bonds that hold dead skin cells together on the skin's surface, lactic acid helps to promote the shedding of these cells, revealing fresher, brighter skin underneath. This exfoliation process not only improves skin texture and tone but also stimulates cell renewal.

One of the key advantages of lactic acid over other AHAs is its moisturizing capability. Lactic acid helps to increase the skin's natural moisturizing factors (NMF), which are essential for keeping the skin hydrated. Its unique ability to draw moisture into the skin makes it particularly beneficial for treating dry and dehydrated skin conditions.

Physiological Effects of Lactic Acid
  1. Exfoliation: A gentle exfoliant that removes dead skin cells from the skin's surface, promoting smooth skin.
  2. Moisture Retention: It is a humectant, meaning it helps the skin retain moisture, improving hydration and reducing dryness.
  3. Collagen Stimulation: Lactic acid can stimulate collagen production in the deeper layers of the skin, aiding in skin firmness and reducing the appearance of fine lines and wrinkles.
  4. Skin Brightening: It helps in lightening dark spots and evening out skin tone, making it effective in treating hyperpigmentation.
  5. pH Balancing: Lactic acid can help balance the skin's natural pH levels, which is beneficial for maintaining a healthy skin barrier.
Role in Managing Dermatological Skin Conditions
  1. Aging Skin: Its collagen-stimulating and exfoliating properties make lactic acid effective in anti-aging treatments, reducing signs of aging like wrinkles and age spots.
  2. Acne-Prone Skin: By unclogging pores and removing dead skin cells, lactic acid can help reduce acne breakouts.
  3. Dry Skin (Xerosis): Its humectant properties are beneficial in hydrating and relieving dry skin.
  4. Hyperpigmentation: Lactic acid is used to treat hyperpigmentation issues, including melasma and sun damage.
  5. Keratosis Pilaris: It can help in managing keratosis pilaris by exfoliating the excess keratin that blocks hair follicles.
References
  • Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
  • Stiller, M. J., et al. (1996). Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin. A double-blind vehicle-controlled clinical trial. Archives of Dermatology.
  • Rawlings, A. V., Davies, A., Carlomusto, M., Pillai, S., Zhang, K., Kosturko, R., ... & Watson, D. (1996). Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function. Archives of Dermatological Research, 288(7), 383-390.
Glycolic acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. It’s celebrated for its small molecular size, which enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to easily penetrate the upper layers of the skin. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as it helps to increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported the role of glycolic acid in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with regular use of glycolic acid.

Physiological Effects of Glycolic acid
  1. Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
  2. Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps in reducing the appearance of fine lines and wrinkles.
  3. Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, leading to enhanced hydration and a more plump, vibrant skin appearance.
  4. Skin Brightening: By removing dead skin cells, it can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
  5. Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even-textured skin, making it beneficial for conditions like keratosis pilaris.
  6. Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.
Role in Managing Dermatological Conditions
  1. Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging such as fine lines, wrinkles, and age spots.
  2. Acne-Prone Skin: It helps in managing acne by exfoliating the skin and keeping pores clear of blockages.
  3. Hyperpigmentation: It is effective in treating hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
  4. Textural Irregularities: Glycolic acid can improve skin texture, making it beneficial for conditions like keratosis pilaris and rough skin.
  5. Sun-Damaged Skin: It helps in rejuvenating sun-damaged skin by accelerating cell turnover and collagen synthesis.
References
  • Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
  • Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
  • Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.
Emollients

Emollients play a crucial role in dermatological care, primarily by enhancing skin hydration and barrier function. Here's a brief overview of their physiological effects and roles in managing various skin conditions:

Physiological Effects of Emollients:
  1. Hydration of Stratum Corneum: Emollients increase moisture content in the stratum corneum, the outermost layer of the skin, by reducing transepidermal water loss (TEWL). This is achieved through occlusion, which traps water in the skin.
  2. Restoration of Skin Barrier Function: They aid in replenishing the lipid barrier of the skin, which is essential for maintaining skin integrity and protective function.
  3. Soothing and Smoothing Effects: Emollients smooth flaky skin cells, making the skin surface appear smoother. They also provide a soothing effect, which can reduce itching and discomfort.
  4. Anti-inflammatory Properties: Some emollients have ingredients that offer mild anti-inflammatory benefits, helping to reduce redness and irritation.
Role in Managing Dermatological Conditions:
  1. Atopic Dermatitis (Eczema): Emollients are a cornerstone in the management of eczema, helping to maintain skin hydration, reduce flare-ups, and minimize the need for topical corticosteroids.
  2. Psoriasis: Regular use of emollients can reduce scaling and dryness associated with psoriasis, improving the efficacy of other topical treatments.
  3. Ichthyosis and Xerosis: These conditions characterized by dry, scaly skin benefit significantly from emollients, which help in hydrating and softening the skin.
  4. Aging Skin: Emollients improve the appearance of aging skin by hydrating and reducing the visibility of fine lines and wrinkles.
  5. Skin Protection: In individuals with incontinence or those bedridden, emollients can protect the skin from irritation and breakdown.
References
  • Proksch, E., & Lachapelle, J. M. (2005). The Management of Dry Skin with Topical Emollients. American Journal of Clinical Dermatology.
  • Lynde, C. W. (2001). Moisturizers: What They Are and a Practical Approach to Product Selection. Skin Therapy Letter.
  • Lodén, M. (2003). Role of Topical Emollients and Moisturizers in the Treatment of Dry Skin Barrier Disorders. American Journal of Clinical Dermatology.
DermExcel™ | Dermalytic
Dermalytic Sale priceR 305.00 ZAR
  • Corns and Calluses: These are thick, hardened layers of skin that develop when your skin tries to protect itself against friction and pressure. Dermalytic softens and exfoliates thickened skin areas, commonly found on hands and feet.
  • Dry Skin (Xerosis): Restore moisture to dry skin and improve its overall texture and appearance.
  • Keratosis Pilaris: Manage this condition characterized by rough, small bumps on the skin.
  • Ichthyosis vulgaris: This is a genetic skin disorder causing dry, scaly skin. The keratolytic properties of Dermalytic may help alleviate the symptoms.
  • Psoriasis: A chronic skin condition that causes cells to build up rapidly on the surface of the skin, forming scales and red patches that are sometimes painful. Dermalytic's keratolytic properties help to soften and remove these scales.
  • Actinic keratosis: A rough, scaly patch on the skin that develops from years of exposure to the sun. The exfoliating and moisturizing properties of Dermalytic is beneficial in managing this condition.
  • Rough skin and uneven skin tone: Stimulates cellular turnover, leading to improved skin texture and more even skin tone.
  • Aging and sun-damaged skin: Exfoliate the skin, stimulate new skin cell production and collagen synthesis.
  • Shaving Bumps and Ingrown Hair on the body: Soothe shaving bumps and prevent ingrown hairs by exfoliating the skin and preventing pore clogging.

Active ingredients

  • Urea
  • Lactic acid
  • Glycolic acid
  • Emollients

Full ingredient list

Aqua, Propylene glycol, Glycolic acid, Salicylic acid, Glycerin, Polyacrylamide & C13-14 Isoparaffin & Laureth-7, Triethanolamine, Hydroxyethylcellulose, Potassium hydroxide

AREA OF APPLICATION:

  • Apply to dry, cracked, hardened, or callused areas: Heels, Elbows, and Knees. For best results on heels - apply Dermalytic at night and wear heel guards to cover the area for at least an hour or overnight.
  • Apply to areas with keratosis pilaris bumps and/or ingrown hair: Upper legs, Upper arms.
  • Apply to areas with body acne: Chest, Back
  • Do not apply Dermalytic to open wounds.

FREQUENCY OF APPLICATION:

  • Dry, cracked, hardened or callused Heels, Elbows, and Knees: Apply every morning and/or evening as tolerated by your skin.
  • Keratosis pilaris bumps and/or ingrown hair on Upper legs and Upper arms: Start by applying twice weekly. Slowly increase the frequency of use as tolerated by your skin.

IMPORTANT:

  • Do not apply Dermalytic on your face. Dermalytic is too potent for facial use.
  • If you use Dermalytic for the above-indicated areas and want to use it on your bikini line, be careful when applying it to the area. Apply a minimal amount, no more than once a week. You can later increase the frequency of use on this bikini-line area as needed and tolerated by your skin.
  • Always apply SPF 30 or above during the day to areas not covered by your clothes.

Dermalytic

benefits

Callus removal

Strong keratolytic action that softens and reduces the thickness of calluses, promoting a smoother and more comfortable skin surface.

Smooth skin texture

Exfoliating dead skin cells and moisturizing the skin will smooth rough patches, revealing a more refined and healthier-looking complexion.

Exfoliating

Remove dead skin cells, and reveal brighter, more radiant skin cells.

Anti-Aging

Supports skin cell renewal and helps improve the appearance of aging by revitalizing and repairing the skin.

Dermalytic

INDICATIONS

Body Acne / Breakouts

Corns and Calluses

Dry & Dehydrated Skin

Dull & Lifeless Skin

Folliculitis

Keratosis Pilaris

Aging Body Skin

Dry and Cracked Heels

Dermalytic

MODE OF ACTION

Exfoliators

testimonials


Customer Reviews

Based on 436 reviews
95%
(413)
4%
(19)
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(4)
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Y
Yolande Barradas
Glycolic Gel

Amazing products.
I have been using DERMALHEALTH for more than 2 years and will never use any other product on my skin again. My skin is glowing and pigmentation marks has visibly reduced. I only use now the Lightweight Foundation in the day, and minimal make-up and for my age (53).... my skin looks and feel amazing!!!
I use the Retinol and Lithaderm serum as well.
The serums last long and a little goes a long way.
Thank you DERMALHEALTH - your customer service is super and delivery of products within a day or 2 to my front door always with a little gift 🤩💜

L
Leone Koekemoer

The BEST!!!

S
Sonja Alberts
Salicilyc gel

Great products!!

Z
Zanele Shweni
Radiant skin

Best decision I made. My skin is radiant everyday. It's like I'm doing daily facials. I look fresh and young.

J
Joadri Matthee
Great product

Works great on blemishes

L
Lizaan Kloppers
Totally love it.

The best product for breakouts and preventing clogged pores. I can’t go a day without it.

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