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Sale price₦93,300.00 NGN



A cutting-edge product formulated to restore the skin barrier function on a physiological level. With its Triple Physiological Lipid-based Technology, this ultra-advanced formula combines various moisturizing agents to create an intelligent moisturizing complex.

It contains patented intelligent hydration technology that operates through a dual mechanism to optimize skin moisturization. Firstly, it forms an intelligent structural layer on the skin's surface, providing immediate hydration and sealing in moisture. Secondly, it regulates water loss from within by reinforcing the skin's natural barrier, preventing excessive moisture evaporation.

Enriched™ is particularly effective for individuals with very dry skin conditions such as eczema, dermatitis, psoriasis, and ichthyosis. By replenishing the skin's essential lipids and lamellar bilayers, this intensely moisturizing complex promotes optimal recovery for dry skin and aids in repairing impaired barrier function.

The results of using Enriched™ are remarkable. Your skin will experience a newfound smoothness with deep hydration that lasts. Moreover, your skin’s resilience will improve, allowing it to withstand external aggressors better and maintain optimal health.

Essential Fatty Acids

Essential Fatty Acids: Nourishing Your Skin from Within

In the realm of dermatological science, essential fatty acids (EFAs) have emerged as unsung heroes, offering a multifaceted approach to improving skin health in patients with conditions such as eczema and dry skin. 

Biochemical Brilliance

Essential fatty acids, including omega-3 and omega-6, are the building blocks of the skin's lipid barrier. This barrier acts as a protective shield, preventing excessive moisture loss and shielding the skin from external aggressors. EFAs play a pivotal role in maintaining this barrier's integrity by contributing to the synthesis of ceramides and lipids that bind skin cells together.

Pharmacological Advantages

EFAs are not only instrumental in maintaining the skin's structural integrity but also possess anti-inflammatory properties. They serve as precursors for pro-resolving lipid mediators like resolvins and protectins, which help reduce skin inflammation, itching, and redness—common symptoms of eczema.

Physiological Harmony

EFAs contribute to maintaining the balance of skin hydration. They enhance the skin's ability to retain water, leaving it supple and hydrated. Moreover, EFAs can modulate the skin's immune response, reducing the severity of allergic reactions and flare-ups often seen in dermatological conditions like eczema.

  1. Elias, P. M. et al. (2008). Skin diseases associated with decreased epidermal lipogenesis. Annals of the New York Academy of Sciences, 1141(1), 1-13.
  2. Ziboh, V. A. et al. (2000). Biochemical basis of the essential fatty acid requirement for normative growth in neonatal baboons. American Journal of Clinical Nutrition, 71(1), 3-11.
  3. Serhan, C. N. (2014). Pro-resolving lipid mediators are leads for resolution physiology. Nature, 510(7503), 92-101.
  4. Levesque, A. et al. (2018). Omega-3 fatty acids: Anti-inflammatory and skin barrier benefits. Omega-3 Fatty Acids: Keys to Nutritional Health, 303-315.
  5. Nicolaou, A. (2013). Eicosanoids in skin inflammation. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 88(1), 131-138.
  6. Meydani, S. N. et al. (2018). Nutrition interventions in aging and age-associated diseases. Annals of the New York Academy of Sciences, 1418(1), 34-51.

d-Panthenol's multifaceted effects on skin hydration, barrier strengthening, and wound healing make it a valuable component in the management of various dermatological conditions, from dry skin to post-procedure care.

d-Panthenol, also known as pro-vitamin B5, is a popular dermatological ingredient due to its beneficial effects on the skin. Here's a brief overview of its physiological effects and roles in managing various skin conditions:

Physiological Effects of d-Panthenol:
  1. Hydration: d-Panthenol is a humectant, meaning it helps to attract and retain moisture in the skin. This leads to increased skin hydration, which can improve skin softness and elasticity.
  2. Wound Healing and Repair: It plays a role in the synthesis of lipids and proteins, essential for skin repair. d-Panthenol has been shown to accelerate re-epithelialization in wound healing.
  3. Anti-Inflammatory Effect: d-Panthenol can reduce inflammation, making it beneficial in treating skin irritations and erythema.
  4. Skin Barrier Strengthening: By enhancing the synthesis of lipids and proteins, d-Panthenol contributes to the strengthening of the skin's barrier function, protecting against irritants and environmental damage.
  5. Soothing and Softening: It soothes the skin and makes it feel softer and smoother, which can be particularly beneficial for dry or rough skin textures.
Role in Managing Dermatological Conditions:
  1. Minor Wounds and Skin Irritations: Due to its role in skin repair and anti-inflammatory properties, d-Panthenol is used in the treatment of minor wounds, cuts, and skin irritations.
  2. Dermatitis and Eczema: It helps in managing conditions like dermatitis and eczema by reducing inflammation and enhancing skin barrier function.
  3. Dry Skin Conditions (Xerosis): Its moisturizing properties make it effective in treating dry skin, providing relief from itching and scaling.
  4. Post-procedure Care: d-Panthenol is often used in post-procedure care, such as after laser treatments or chemical peels, to aid in skin recovery and reduce inflammation.
  • Proksch, E., & Nissen, H. P. (2002). Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation. Journal of Dermatological Treatment.
  • Ebner, F., Heller, A., Rippke, F., & Tausch, I. (2002). Topical use of dexpanthenol in skin disorders. American Journal of Clinical Dermatology.
  • Camargo, F. B. Jr, Gaspar, L. R., & Maia Campos, P. M. B. G. (2011). Skin moisturizing effects of panthenol-based formulations. Journal of Cosmetic Science.

Medilan™'s unique formulation and hypoallergenic properties make it a valuable component in the management of various dermatological conditions, particularly for hydrating and soothing sensitive and dry skin.

Medilan™, a ultra-refined, hypoallergenic medical grade lanolin, has proven to be very beneficial for managing dermatological conditions. Below is a brief overview of its physiological effects and roles in managing various skin conditions:

Physiological Effects of Medilan™
  1. Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
  2. Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
  3. Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
  4. Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
  5. Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
  6. Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
  7. Skin Penetration and Hydration: It has the ability to penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
  8. Occlusive Properties: Medilan™ helps in reducing transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.
Role in Managing Dermatological Conditions:
  1. Eczema and Dry Skin Conditions: Due to its soothing, hydrating, and occlusive properties, Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions.
  2. Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in the healing of minor wounds and skin irritations.
  3. Sensitive Skin Care: Its hypoallergenic nature makes it suitable for use in individuals with sensitive skin, reducing the risk of irritation or allergic reactions.
  4. Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
  5. Chapped Lips and Skin: It is effective in treating chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.
  • Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
  • Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
  • DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
  • Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing​​.
  • ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy​​.

Niacinamide offers several benefits for the skin, primarily due to its anti-inflammatory and antioxidant properties. It reduces the redness and inflammation associated with acne, rosacea, and other inflammatory skin conditions. Additionally, niacinamide's ability to improve the skin's barrier function benefits all skin types, particularly those with eczema or mature skin.

Another significant benefit of niacinamide is its role in reducing hyperpigmentation. Studies have shown that it can decrease the transfer of melanin to the epidermis, helping to fade dark spots and even out skin tone.

Niacinamide also plays a role in reducing the visible signs of aging. It has been found to stimulate collagen production and improve skin elasticity, reducing fine lines and wrinkles. Its antioxidant properties further protect the skin from environmental damage, such as pollution and UV radiation, which contribute to premature aging.

The efficacy of niacinamide and its ability to address multiple skin concerns simultaneously has led to its growing popularity in both over-the-counter and prescription skincare formulations.


Ceramides, a family of lipid molecules naturally present in the skin, are integral to the structure and function of the skin barrier. They are a type of lipid that, along with cholesterol and fatty acids, forms a critical part of the stratum corneum, the outermost layer of the skin. This layer is essential for maintaining skin hydration and protecting against environmental aggressors.

Ceramides, which make up about 50% of the skin's lipid composition, play a pivotal role in maintaining the skin's barrier integrity and preventing transepidermal water loss (TEWL). By doing so, they help keep the skin hydrated and supple.

The loss or reduction of ceramides in the skin barrier is associated with several dermatological conditions, including eczema and psoriasis, where the skin becomes dry, itchy, and prone to irritation and infection. Studies have shown that the application of ceramide-containing moisturizers can effectively improve skin barrier function and increase skin hydration levels.

Ceramides are particularly beneficial for aging skin, which naturally loses ceramides over time, leading to drier and more fragile skin. By replenishing the skin's ceramide content, these products can help combat the signs of aging, such as fine lines and wrinkles.

Ceramides are integral to maintaining skin health, particularly in conditions where the skin barrier is compromised. Their role in hydrating the skin, reducing sensitivity, and improving barrier function makes them an essential component in the management of various dermatological conditions, especially eczema, psoriasis, and dry or aging skin.

Physiological Effects of Ceramides
  1. Barrier Function: Ceramides are critical components of the skin's lipid barrier. They help to prevent moisture loss and protect against environmental aggressors like pollutants and irritants.
  2. Hydration: By maintaining the barrier integrity, ceramides keep the skin hydrated, preventing dryness and keeping the skin supple.
  3. Reducing Skin Sensitivity: They play a role in reducing skin sensitivity and irritation, helping to calm inflamed and reactive skin.
  4. Anti-aging Properties: Ceramides can improve skin elasticity and firmness, helping to reduce the appearance of fine lines and wrinkles.
  5. Wound Healing: There is evidence to suggest that ceramides can aid in the skin's natural wound healing process.
Role in Managing Dermatological Conditions
  1. Eczema and Atopic Dermatitis: Ceramides are often used in the treatment of eczema and atopic dermatitis, where the skin barrier is compromised, leading to dryness, itching, and inflammation.
  2. Psoriasis: They can help in managing psoriasis by maintaining skin hydration and barrier function, reducing scaling and dryness.
  3. Aging Skin: Ceramide-containing products are beneficial in anti-aging regimens due to their ability to improve skin barrier function and elasticity.
  4. Dry Skin (Xerosis): In the treatment of dry skin, ceramides help in restoring skin hydration and barrier function.
  5. Sensitive Skin: Products containing ceramides are suitable for sensitive skin as they help to restore the skin's natural barrier and reduce irritation.
  • Del Rosso, J. Q., & Levin, J. (2011). The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin. Journal of Clinical and Aesthetic Dermatology.
  • Farwanah, H., Wohlrab, J., Neubert, R. H. H., & Raith, K. (2005). Ceramides and skin function. American Journal of Clinical Dermatology.
  • Di Nardo, A., Wertz, P., Giannetti, A., & Seidenari, S. (1998). Ceramide and cholesterol composition of the skin of patients with atopic dermatitis. Acta Dermato-Venereologica.
DermExcel™ | Enriched
Enriched Sale price₦93,300.00 NGN
  • Eczema: Help alleviate the symptoms of eczema, including itching, redness, inflammation, and dry patches.
  • Dry Skin (Xerosis): Provides intense hydration to address the symptoms of dry skin, such as tightness, roughness, and flakiness.
  • Dermatitis: Beneficial for various types of dermatitis, such as contact dermatitis, atopic dermatitis, and seborrheic dermatitis. It helps soothe irritated skin and supports the healing process.
  • Psoriasis: Aids in the management of psoriasis by moisturizing the skin, reducing redness, and supporting the skin's natural barrier function.
  • Ichthyosis: Effective in addressing the scaling, roughness, and excessive dryness associated with ichthyosis, a genetic disorder that impairs the skin's ability to retain moisture.
  • Impaired barrier function: The product aids in restoring the physiological barrier function of the skin, which can be compromised due to various factors such as aging, environmental stressors, or certain skin conditions.

Time of application: Apply in the morning and/or evening on cleansed skin after treatment serums.

Frequency of application: Use daily and/or evening or follow your Dermal Diagnosis treatment plan directions.

Apply Enriched to damp skin. Moisturizers are most effective if you use them while your skin is damp because damp skin absorbs the product more readily. That also gives the moisturizer a chance to lock in that hydration.

Active ingredients

  • Essential Fatty Acids
  • d-Panthenol
  • Medilan™
  • Nc4
  • Ceramides

Full ingredient list

Aqua, white soft paraffin, extra pure lanolin, emulsifying wax, glycerin, stearic acid, ceramides, cholesterol, liquid paraffin, niacinamide, cetyl alcohol, cetomacrogol, isostearyl isostearate, potassium cetyl phosphate, cetyl stearate, stearic acid, ethyl hexyl glycerin, phenoxyethanol, carbomer, d-panthenol, sodium hyaluronate, C12-17 alkane, triethanolamine.



Intense hydration

Increase the moisture content of the epidermis, contributing to skin elasticity and suppleness.

Rich in emollients

Fill the gaps between skin cells and replace missing lipids - making the skin feel softer and smoother.

Creates protective layer

Creates a protective layer on top of the skin to prevent water loss and to lock in moisture.

Itching Relief

Providing relief from itching and discomfort, reduces scratching and prevents further skin damage and potential infections.

Promote Cell Renewal

Creates the ideal skin environment to optimize cellular processes and turnover to ensure a vibrant and youthful appearance.

Barrier Repair

Physiological barrier repair with lipid-based, ceramide-dominant therapy, enabling the skin to protect itself from environmental stressors and pathogens.



  • Skin that feels and looks rough and dry
  • Dull skin tone
  • Flaking skin, which may cause an ashy appearance
  • A feeling of skin tightness
  • Itchy uncomfortable skin

Optimal skin barrier vs.

Disrupted skin barrier




Enriched mode of action

moisturizing & barrier repair

  • Lipid Bilayer Technology amplifies lipid production and replenish the lamellar bilayers that are critical for normal barrier function and antimicrobial defence.
  • They are quickly absorbed into the underlying nucleated cell layers, where they incorporate into lamellar bodies.
  • This Barrier Repair Therapy furthermore reduce inflammation by several mechanisms, leading to a smoother surface with less friction and greater light refraction.

Replenish lipid bilayers critical for normal barrier function.

  • Emollients soften and smooth the skin. They function by filling the gaps between skin cells and replace missing lipids.
  • They function by filling the gaps between skin cells and replacing the missing lipids.
  • Emollients flatten the curled edges of the individual skin cells (corneocytes), leading to a smoother surface with less friction and greater light refraction.

Fill the gaps between skin cells and replace missing lipids.

  • Humectants are water-soluble materials with high water absorption capabilities.
  • They draw moisture from the air into the skin and/or draw moisture from the dermis into the epidermis.
  • Humectants can help to diminish the appearance of fine lines and wrinkles by plumping up the skin, giving it a more youthful appearance.

Attract water to the skin to maintain its moisture balance.

  • Creates a protective layer on top of the skin that locks in moisture and prevent transepidermal water loss (TEWL).
  • The barrier formed by occlusives also protects the skin from external irritants such as pollutants, allergens, and harsh weather conditions, contributing to skin sensitivity and damage.
  • For dry, cracked, or irritated skin, occlusives provide immediate relief by covering the affected area and preventing further moisture loss, allowing the skin to heal more effectively.

Creates a protective layer on top of skin to lock moisture in.



Customer Reviews

Based on 462 reviews
Nulandi Coetzee
Best product ever

I am using DermNourish in summer and it is perfect, but when winter comes I add Enriched to my skincare regime. Enriched is absolutely fantastic. My skin stays so soft all winter long. Thank you to Dermexel for the exelent product range.

Marie-louise Pietersen


Feeling Fresh

I’ve been in the products for the past 6 months. Amazing results. I stuggle with acne and scaring. Have now seen much improvement. Love it. Ps. The lip balm is the best

Ann-Marie Piquita
Exceptional product

Hydrating & moisturizing, leaves skin feeling great!

Elsabe Immelman

Best product I have ever used...






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