DermExcel™

Enriched

4.9 / 5.0 from 503 reviews

L£5,887,000.00

Size:

Variant

irritated skin

aging

Dry skin

Inflammation

Allergies

A cutting-edge product formulated to restore the skin barrier function on a physiological level. With its Triple Physiological Lipid-based Technology, this ultra-advanced formula combines various moisturizing agents to create an intelligent moisturizing complex.

It contains patented intelligent hydration technology that operates through a dual mechanism to optimize skin moisturization. Firstly, it forms an intelligent structural layer on the skin's surface, providing immediate hydration and sealing in moisture. Secondly, it regulates water loss from within by reinforcing the skin's natural barrier, preventing excessive moisture evaporation.

Enriched™ is particularly effective for individuals with very dry skin conditions such as eczema, dermatitis, psoriasis, and ichthyosis. By replenishing the skin's essential lipids and lamellar bilayers, this intensely moisturizing complex promotes optimal recovery for dry skin and aids in repairing impaired barrier function.

The results of using Enriched™ are remarkable. Your skin will experience a newfound smoothness with deep hydration that lasts. Moreover, your skin’s resilience will improve, allowing it to withstand external aggressors better and maintain optimal health.

Ceramides

Ceramides, a family of lipid molecules naturally present in the skin, are integral to the structure and function of the skin barrier. They are a type of lipid that, along with cholesterol and fatty acids, forms a critical part of the stratum corneum, the outermost layer of the skin. This layer is essential for maintaining skin hydration and protecting against environmental aggressors.

Ceramides, which make up about 50% of the skin's lipid composition, play a pivotal role in maintaining the skin's barrier integrity and preventing transepidermal water loss (TEWL). By doing so, they help keep the skin hydrated and supple.

The loss or reduction of ceramides in the skin barrier is associated with several dermatological conditions, including eczema and psoriasis, where the skin becomes dry, itchy, and prone to irritation and infection. Studies have shown that the application of ceramide-containing moisturizers can effectively improve skin barrier function and increase skin hydration levels.

Ceramides are particularly beneficial for aging skin, which naturally loses ceramides over time, leading to drier and more fragile skin. By replenishing the skin's ceramide content, these products can help combat the signs of aging, such as fine lines and wrinkles.

Ceramides are integral to maintaining skin health, particularly in conditions where the skin barrier is compromised. Their role in hydrating the skin, reducing sensitivity, and improving barrier function makes them an essential component in the management of various dermatological conditions, especially eczema, psoriasis, and dry or aging skin.

Physiological Effects

Barrier Function: Ceramides are critical components of the skin's lipid barrier. They help to prevent moisture loss and protect against environmental aggressors like pollutants and irritants.
Hydration: By maintaining the barrier integrity, ceramides keep the skin hydrated, preventing dryness and keeping the skin supple.
Reducing Skin Sensitivity: They play a role in reducing skin sensitivity and irritation, helping to calm inflamed and reactive skin.
Anti-aging Properties: Ceramides can improve skin elasticity and firmness, helping to reduce the appearance of fine lines and wrinkles.
Wound Healing: There is evidence to suggest that ceramides can aid in the skin's natural wound healing process.

Role in Managing Dermatological Conditions

Eczema and Atopic Dermatitis: Ceramides are often used in the treatment of eczema and atopic dermatitis, where the skin barrier is compromised, leading to dryness, itching, and inflammation.
Psoriasis: They can help in managing psoriasis by maintaining skin hydration and barrier function, reducing scaling and dryness.
Aging Skin: Ceramide-containing products are beneficial in anti-aging regimens due to their ability to improve skin barrier function and elasticity.
Dry Skin (Xerosis): In the treatment of dry skin, ceramides help in restoring skin hydration and barrier function.
Sensitive Skin: Products containing ceramides are suitable for sensitive skin as they help to restore the skin's natural barrier and reduce irritation.

References

Del Rosso, J. Q., & Levin, J. (2011). The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin. Journal of Clinical and Aesthetic Dermatology.
Farwanah, H., Wohlrab, J., Neubert, R. H. H., & Raith, K. (2005). Ceramides and skin function. American Journal of Clinical Dermatology.
Di Nardo, A., Wertz, P., Giannetti, A., & Seidenari, S. (1998). Ceramide and cholesterol composition of the skin of patients with atopic dermatitis. Acta Dermato-Venereologica.

Niacinamide

Niacinamide offers several benefits for the skin, primarily due to its anti-inflammatory and antioxidant properties. It reduces the redness and inflammation associated with acne, rosacea, and other inflammatory skin conditions. Additionally, niacinamide's ability to improve the skin's barrier function benefits all skin types, particularly those with eczema or mature skin.

Another significant benefit of niacinamide is its role in reducing hyperpigmentation. Studies have shown that it can decrease the transfer of melanin to the epidermis, helping to fade dark spots and even out skin tone.

Niacinamide also plays a role in reducing the visible signs of aging. It has been found to stimulate collagen production and improve skin elasticity, reducing fine lines and wrinkles. Its antioxidant properties further protect the skin from environmental damage, such as pollution and UV radiation, which contribute to premature aging.

The efficacy of niacinamide and its ability to address multiple skin concerns simultaneously has led to its growing popularity in both over-the-counter and prescription skincare formulations.

Physiological Effects

Barrier Function Enhancement: Niacinamide helps strengthen the skin’s barrier function by increasing the production of ceramides, lipids that keep the skin hydrated and protect against environmental damage.
Anti-inflammatory Properties: It has notable anti-inflammatory effects, which are beneficial in reducing redness and inflammation associated with acne, eczema, and other inflammatory skin conditions.
Sebum Regulation: Niacinamide helps regulate sebum production, which controls excess oiliness and can benefit acne-prone skin.
Hyperpigmentation Reduction: It reduces hyperpigmentation by inhibiting melanosome transfer from melanocytes to keratinocytes, leading to an even skin tone.
Anti-aging Effects: Niacinamide helps reduce the appearance of fine lines and wrinkles by boosting collagen production and improving skin elasticity.
Antioxidant Activity: It has antioxidant properties, protecting the skin from oxidative stress and environmental aggressors like UV radiation and pollution.

Role in Managing Dermatological Conditions

Acne and Oily Skin: Niacinamide effectively manages acne and oily skin by regulating sebum and reducing inflammation.
Hyperpigmentation and Melasma: Its ability to reduce melanin transfer benefits it in treating hyperpigmentation and melasma.
Aging Skin: Niacinamide targets wrinkles and loss of firmness.
Skin Barrier Disorders: Niacinamide is beneficial in treating skin barrier disorders like atopic dermatitis and eczema by enhancing barrier function and hydration.
Photodamage and Skin Protection: It helps mitigate the effects of photodamage and provides some degree of protection against environmental damage.

References

Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology.
Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery.
Snaidr, V. A., Damian, D. L., & Halliday, G. M. (2019). Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety. Experimental Dermatology.
Navarrete-Solís, J. et al. (2011). A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Dermatology Research and Practice, 2011.

d-Panthenol

d-Panthenol's multifaceted effects on skin hydration, barrier strengthening, and wound healing make it a valuable component in the management of various dermatological conditions, from dry skin to post-procedure care.

d-Panthenol, also known as pro-vitamin B5, is a popular dermatological ingredient due to its beneficial effects on the skin. Here's a brief overview of its physiological effects and roles in managing various skin conditions:

Physiological Effects

Hydration: d-Panthenol is a humectant, meaning it helps to attract and retain moisture in the skin. This leads to increased skin hydration, which can improve skin softness and elasticity.
Wound Healing and Repair: It plays a role in the synthesis of lipids and proteins, essential for skin repair. d-Panthenol has been shown to accelerate re-epithelialization in wound healing.
Anti-Inflammatory Effect: d-Panthenol can reduce inflammation, making it beneficial in treating skin irritations and erythema.
Skin Barrier Strengthening: By enhancing the synthesis of lipids and proteins, d-Panthenol contributes to the strengthening of the skin's barrier function, protecting against irritants and environmental damage.
Soothing and Softening: It soothes the skin and makes it feel softer and smoother, which can be particularly beneficial for dry or rough skin textures.

Role in Managing Dermatological Conditions

Minor Wounds and Skin Irritations: Due to its role in skin repair and anti-inflammatory properties, d-Panthenol is used in the treatment of minor wounds, cuts, and skin irritations.
Dermatitis and Eczema: It helps in managing conditions like dermatitis and eczema by reducing inflammation and enhancing skin barrier function.
Dry Skin Conditions (Xerosis): Its moisturizing properties make it effective in treating dry skin, providing relief from itching and scaling.
Post-procedure Care: d-Panthenol is often used in post-procedure care, such as after laser treatments or chemical peels, to aid in skin recovery and reduce inflammation.

References

Proksch, E., & Nissen, H. P. (2002). Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation. Journal of Dermatological Treatment.
Ebner, F., Heller, A., Rippke, F., & Tausch, I. (2002). Topical use of dexpanthenol in skin disorders. American Journal of Clinical Dermatology.
Camargo, F. B. Jr, Gaspar, L. R., & Maia Campos, P. M. B. G. (2011). Skin moisturizing effects of panthenol-based formulations. Journal of Cosmetic Science.

Essential Fatty Acids

Essential Fatty Acids: Nourishing Your Skin from Within

In the realm of dermatological science, essential fatty acids (EFAs) have emerged as unsung heroes, offering a multifaceted approach to improving skin health in patients with conditions such as eczema and dry skin.

Pharmacological Advantages

EFAs are not only instrumental in maintaining the skin's structural integrity but also possess anti-inflammatory properties. They serve as precursors for pro-resolving lipid mediators like resolvins and protectins, which help reduce skin inflammation, itching, and redness—common symptoms of eczema.

Physiological Harmony

EFAs contribute to maintaining the balance of skin hydration. They enhance the skin's ability to retain water, leaving it supple and hydrated. Moreover, EFAs can modulate the skin's immune response, reducing the severity of allergic reactions and flare-ups often seen in dermatological conditions like eczema.

Biochemical Brilliance

Essential fatty acids, including omega-3 and omega-6, are the building blocks of the skin's lipid barrier. This barrier acts as a protective shield, preventing excessive moisture loss and shielding the skin from external aggressors. EFAs play a pivotal role in maintaining this barrier's integrity by contributing to the synthesis of ceramides and lipids that bind skin cells together.

References

Elias, P. M. et al. (2008). Skin diseases associated with decreased epidermal lipogenesis. Annals of the New York Academy of Sciences, 1141(1), 1-13.
Ziboh, V. A. et al. (2000). Biochemical basis of the essential fatty acid requirement for normative growth in neonatal baboons. American Journal of Clinical Nutrition, 71(1), 3-11.
Serhan, C. N. (2014). Pro-resolving lipid mediators are leads for resolution physiology. Nature, 510(7503), 92-101.
Levesque, A. et al. (2018). Omega-3 fatty acids: Anti-inflammatory and skin barrier benefits. Omega-3 Fatty Acids: Keys to Nutritional Health, 303-315.
Nicolaou, A. (2013). Eicosanoids in skin inflammation. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 88(1), 131-138.
Meydani, S. N. et al. (2018). Nutrition interventions in aging and age-associated diseases. Annals of the New York Academy of Sciences, 1418(1), 34-51.

Medilan™

Medilan™'s unique formulation and hypoallergenic properties make it a valuable component in managing various dermatological conditions, particularly for hydrating and soothing sensitive and dry skin.

Medilan™, an ultra-refined, hypoallergenic medical-grade lanolin, has proven to be very beneficial for managing dermatological conditions. Below is a brief overview of its physiological effects and roles in managing various skin conditions.

Physiological Effects

Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
Skin Penetration and Hydration: It can penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
Occlusive Properties: Medilan™ helps reduce transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.

Role in Managing Dermatological Conditions

Eczema and Dry Skin Conditions: Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions due to its soothing, hydrating, and occlusive properties.
Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in healing minor wounds and skin irritations.
Sensitive Skin Care: Its hypoallergenic nature makes it suitable for sensitive skin, reducing the risk of irritation or allergic reactions.
Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
Chapped Lips and Skin: It effectively treats chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.

References

Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing.
ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy.

USE DURING PREGNANCY

Enriched is safe to use during pregnancy.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in USA and Australia, tailored to your shipping address for optimal efficiency.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in the USA and Australia will enjoy delivery within 1-4 business days. International orders will receive their orders from 6 to 25 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

Dermal Health Science Secure Payment Promise: We utilize cutting-edge encryption and security measures to ensure your payment details remain as unblemished as your skin.

Our Secure Payment Promise backs every transaction with DermExcel. We partner with trusted payment providers to create the best shopping experience for you.

Simple. Effective. Ethical. That's not just our skincare philosophy but our approach to your security too.

Enriched

L£5,887,000.00

Eczema: Help alleviate the symptoms of eczema, including itching, redness, inflammation, and dry patches.
Dry Skin (Xerosis): Provides intense hydration to address the symptoms of dry skin, such as tightness, roughness, and flakiness.
Dermatitis: Beneficial for various types of dermatitis, such as contact dermatitis, atopic dermatitis, and seborrheic dermatitis. It helps soothe irritated skin and supports the healing process.
Psoriasis: Aids in the management of psoriasis by moisturizing the skin, reducing redness, and supporting the skin's natural barrier function.
Ichthyosis: Effective in addressing the scaling, roughness, and excessive dryness associated with ichthyosis, a genetic disorder that impairs the skin's ability to retain moisture.
Impaired barrier function: The product aids in restoring the physiological barrier function of the skin, which can be compromised due to various factors such as aging, environmental stressors, or certain skin conditions.

Active ingredients

Ceramides

Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
Skin Penetration and Hydration: It can penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
Occlusive Properties: Medilan™ helps reduce transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.

Eczema and Dry Skin Conditions: Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions due to its soothing, hydrating, and occlusive properties.
Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in healing minor wounds and skin irritations.
Sensitive Skin Care: Its hypoallergenic nature makes it suitable for sensitive skin, reducing the risk of irritation or allergic reactions.
Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
Chapped Lips and Skin: It effectively treats chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.

Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing.
ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy.

Niacinamide

Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
Skin Penetration and Hydration: It can penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
Occlusive Properties: Medilan™ helps reduce transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.

Eczema and Dry Skin Conditions: Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions due to its soothing, hydrating, and occlusive properties.
Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in healing minor wounds and skin irritations.
Sensitive Skin Care: Its hypoallergenic nature makes it suitable for sensitive skin, reducing the risk of irritation or allergic reactions.
Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
Chapped Lips and Skin: It effectively treats chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.

Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing.
ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy.

d-Panthenol

Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
Skin Penetration and Hydration: It can penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
Occlusive Properties: Medilan™ helps reduce transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.

Eczema and Dry Skin Conditions: Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions due to its soothing, hydrating, and occlusive properties.
Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in healing minor wounds and skin irritations.
Sensitive Skin Care: Its hypoallergenic nature makes it suitable for sensitive skin, reducing the risk of irritation or allergic reactions.
Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
Chapped Lips and Skin: It effectively treats chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.

Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing.
ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy.

Essential Fatty Acids

Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
Skin Penetration and Hydration: It can penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
Occlusive Properties: Medilan™ helps reduce transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.

Eczema and Dry Skin Conditions: Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions due to its soothing, hydrating, and occlusive properties.
Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in healing minor wounds and skin irritations.
Sensitive Skin Care: Its hypoallergenic nature makes it suitable for sensitive skin, reducing the risk of irritation or allergic reactions.
Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
Chapped Lips and Skin: It effectively treats chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.

Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing.
ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy.

Medilan™

Emollient: Medilan™ is an excellent emollient, helping to soften and smooth the skin by retaining moisture. It creates an occlusive barrier, which reduces transepidermal water loss (TEWL).
Moisturizing: It is highly effective in moisturizing dry and rough skin, enhancing skin hydration by trapping and sealing in moisture.
Hypoallergenic: Medilan™ is ultra-purified to minimize the risk of allergic reactions, making it suitable for sensitive skin types.
Wound Healing: Medilan™ aids in the healing process of minor cuts, abrasions, and burns by maintaining a moist wound environment.
Skin Barrier Function: It enhances the skin's barrier function, protecting against environmental irritants and reducing the risk of skin infections.
Lipid Replenishment: Medilan™ mimics the lipids found in human skin, helping to restore the lipid barrier of the skin, especially beneficial in dry and chapped skin conditions.
Skin Penetration and Hydration: It can penetrate the skin and aid in water retention in the stratum corneum, the outermost layer of the skin, thus enhancing hydration.
Occlusive Properties: Medilan™ helps reduce transepidermal water loss by forming a barrier on the skin surface, thereby retaining moisture and improving skin barrier function.

Eczema and Dry Skin Conditions: Medilan™ is a valuable ingredient in treating eczema and other dry skin conditions due to its soothing, hydrating, and occlusive properties.
Wound Healing: While primarily used for its emollient effects, the properties of Medilan™ also aid in healing minor wounds and skin irritations.
Sensitive Skin Care: Its hypoallergenic nature makes it suitable for sensitive skin, reducing the risk of irritation or allergic reactions.
Nipple Care in Breastfeeding: Soothes and heals cracked and sore nipples in breastfeeding mothers.
Chapped Lips and Skin: It effectively treats chapped lips and skin, providing a barrier that seals in moisture and protects from harsh weather conditions.

Lodén, M., & Maibach, H. I. (2000). Dry skin and moisturizers: chemistry and function. CRC Press.
Suleman, H., et al. (2000). Role of lanolin in managing eczema and dry skin conditions. Community Nurse.
DiNardo, J. C. (2000). Is lanolin allergy a myth? Dermatitis.
Stone, L. (2000). Medilan: a hypoallergenic lanolin for emollient therapy. British Journal of Nursing.
ResearchGate Article on Medilan™ highlighting its role in skin care and emollient therapy.

Full ingredient list

Aqua, white soft paraffin, extra pure lanolin, emulsifying wax, glycerin, stearic acid, ceramides, cholesterol, liquid paraffin, niacinamide, cetyl alcohol, cetomacrogol, isostearyl isostearate, potassium cetyl phosphate, cetyl stearate, stearic acid, ethyl hexyl glycerin, phenoxyethanol, carbomer, d-panthenol, sodium hyaluronate, C12-17 alkane, triethanolamine.

Morning & / or Evening

Application time: Morning and/or Evening.
Frequency: Use once or twice daily, depending on the severity of skin dryness or sensitivity, or use according to your dermal Diagnosis treatment instructions.

1. Cleanse

Start with clean and dry skin.
Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2. Apply

Dispense moisturizer onto your fingertips. Smooth the product evenly over your face. Ensure you cover all dry or sensitive areas.
Using your fingertips, gently massage the product into your skin in a circular motion until fully absorbed.

Important note

Apply your moisturizer to damp skin. Moisturizers are most effective if you use them while your skin is damp because damp skin absorbs the product more readily. That also gives the moisturizer a chance to lock in that hydration.

Enriched

product benefits

Intense hydration

Shield the skin from external irritants and pollutants by forming a protective barrier, providing continuous hydration, improving skin elasticity, and supporting the skin's natural defense mechanisms.

Itch Relief

It provides relief from itching and discomfort by reducing inflammation. By reducing scratching, it prevents further skin damage and potential infections.

Promote Cell Renewal

It enhances skin regeneration by optimizing cellular processes and stimulating the production of new skin cells which helps to rejuvenate the skin, diminish signs of aging, and enhance skin vitality.

Barrier Repair

Physiological barrier repair by strengthening the skin's structural integrity, reducing sensitivity and increasing the skin's ability to defend against harmful agents

enriched

mode of action

Niacinamide

INHIBIT HYPERPIGMENTATION

Prevents DNA damage through antioxidant activity.
Prevent melanosome transfer from melanocytes to surrounding skin cells.

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TREATING ROSACEA, ACNE AND OTHER INFLAMMATORY SKIN CONDITIONS

Reduce the inflammatory response by inhibiting inflammatory messengers.
Provides long-lasting protection against bacteria through activation of anti-microbial peptides
Reduce sebum (oil) production, thus preventing bacterial growth and inflammation.

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TREATING AND PREVENTING PREMATURE SKIN AGING

Stimulate collagen synthesis and significantly increase skin elasticity.
Prevents the breakdown of collagen and elastin through antioxidant and anti-inflammatory activity.
Prevents DNA damage through antioxidant activity.
Increases production of ceramides and other stratum corneum lipids to improve skin barrier function.
Niacinamide boosts cellular energy and may enhance energy-dependent cellular processes such as DNA repair.

Hyaluronic acid

Hyaluronic acid is a naturally occurring biopolymer possessing numerous functions within the body, including wound repair, cell migration, and cell signalling.
With age, hyaluronic acid in the skin decreases sharply, resulting in a loss of hydration, volume and plumpness. Lines and wrinkles also appear, leaving skin looking dull and lacklustre.
Hyaluronic acid comes in various molecular sizes. Larger molecules stay on the surface and give the skin a ‘dewy’ look, while smaller molecules penetrate deeper into the skin to deliver their hydration and plumping benefits.
The cellular and physiological effects of Hyaluronic acid directly depend on the molecular weight of HA present. Therefore, the selection of HA weight is of critical importance.
The cellular and physiological effects of Hyaluronic acid directly depend on the molecular weight of HA present. Therefore, the selection of HA weight is of critical importance.
High molecular weight: Doesn't penetrate the epidermis.
Very low molecular weight: Penetrate the skin efficiently but can induce a pro-inflammatory response.
Low molecular weight HA [50 kDa]: Penetrates into the skin well and does not cause inflammation.

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HYDRATION

Hyaluronic acid can bind water up to 1000 times its volume and contributes to cellular growth, adhesion, and membrane receptor function.
Hyaluronic acid reinforces the intercellular structures and produces the elastoviscous fluid matrix that firmly envelops collagen and elastin fibres.
Hyaluronic acid holds moisture and provides firmness and radiance to the skin.

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ANTI-AGING

Hyaluronic acid increases pro-collagen I synthesis and reduce skin roughness.
Hyaluronic acid has an important role in skin aging. Cells lose their ability to produce Hyaluronic acid with aging. The skin becomes drier, thinner, and looser, leading to wrinkling, among other significant changes.
Skin aging is also associated with a decrease of skin moisture. Hyaluronic acid has a unique capacity to link and retain water molecules. Hyaluronic acid is a natural component that is present in the whole body. It is naturally and constantly renewed because of its rapid degradation, but its renewal tends to slow with age and external aggressions. Therefore it is necessary to act very early, sustaining an optimal hyaluronic acid turnover, similar to that of young skin, in order to prevent the signs of aging.
In relation to its biological effects at the skin level, it is known that hyaluronic acid is actively involved in skin cell signalling (by binding the CD44 and LYVE-1 receptors) and thus influences the extracellular matrix (ECM) stability.
Hyaluronic acid has an impact on the growth of keratinocytes (skin cells) which protect the epidermis from aging and promotes elasticity.

Medilan™

KEY BENEFITS

Medilan imitates many functions of human skin lipids, which is nearly twice as effective as the physiological lipids in human skin.

Medilan™ has clinically proven safety and efficacy. It is designed to treat skin barrier impairment and severely compromised skin conditions such as rosacea, eczema, and psoriasis. Its exceptional purity surpasses monograph compliance and performs excellently in clinical trials.

In clinical trials, Medilan maintains skin hydration for up to 2 days after application and increases the rate of epidermal healing by 35% due to its ability to create a moist wound-healing environment.

Medilan™ is hypoallergenic and delivers outstanding efficacy in dermatological applications. Studies have shown no allergic or irritant skin reactions to Medilan, even in severely compromised skin.

Lanolin's efficacy as a medical material and acceptance in the Pharmaceutical Industry is reflected in all major Pharmacopeia containing monographs on lanolin.

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REPLENISHING ESSENTIAL LIPIDS

Medilan™ supplements the skin with the lipids essential to skin health.

Due to its chemical and physical similarity, it imitates and augments many of the skin's natural lipids.

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REPAIRING THE SKIN’S NATURAL BARRIER

Medilan™ effectively accelerates the repair of the skin’s natural barrier function.

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PROTECTING AGAINST MICROBIAL INFECTION

Medilan is proven to control a variety of microorganisms.

Staphylococcus aureus is a gram-positive bacteria responsible for the infection that leads to inflammatory symptoms in eczema sufferers. Medilan has been proven to reduce colonies of this bacteria by 99% after 24 hours.
Candidiasis is an overgrowth of yeast that leads to unpleasant symptoms, such as itching and soreness around the skin's mucous membranes. Medilan has been proven to reduce the levels of Candida albicans to a level that controls candidiasis symptoms.
Pseudomonas aeruginosa is a gram-negative bacteria that can attack wound sites and lead to infection. Wound infection is common in immunocompromised individuals. Medilan has shown potent antibacterial effects against this organism.

d-Panthenol

D-Panthenol stimulates the proliferation of dermal fibroblasts and can accelerate cell turnover.

WOUND HEALING

D-Panthenol is used in medical wound-healing formulations to help treat skin injuries, burns, and sunburn.
It's also beneficial after medical and cosmetic surgeries for its wound-healing properties.
It treats superficial and deep wounds by increasing cell turnover and fibroblast proliferation.

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REPAIR SKIN BARRIER FUNCTION

D-Panthenol promotes skin barrier repair by enhancing lipid synthesis and epidermal differentiation. This helps hydrate the outermost layer of the skin and locks in moisture.
D-Panthenol increases the mobility of proteins and lipids in dehydrated skin, improving its elasticity and hydration.

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ANTI-INFLAMMATORY

Panthenol’s moisturizing properties also contribute to its anti-inflammatory nature.
Keeping the skin moisturized can help prevent it from becoming sensitive and easily irritated. As such, panthenol can help improve the roughness, dryness, itching, redness, and scaling associated with conditions such as eczema, contact dermatitis, and psoriasis.
Studies indicate that D-Panthenol may alleviate facial redness from winter xerosis in people with sensitive skin.

Glycerin

Humectant. It allows the skin to retain moisture. It increases skin hydration, relieves dryness, and refreshes the skin’s surface.
Emollient. Soften rough or dry patches on the skin.
Anti-microbial. It helps to protect the skin from harmful microorganisms.

Fatty acids

Essential fatty acids (EFAs) offer a multifaceted approach to improving skin health in patients with eczema and dry skin conditions.

BIOCHEMICAL BRILLIANCE

Essential fatty acids, including omega-3 and omega-6, are the building blocks of the skin's lipid barrier. This barrier is a protective shield, preventing excessive moisture loss and shielding the skin from external aggressors. EFAs play a pivotal role in maintaining this barrier's integrity by contributing to the synthesis of ceramides and lipids that bind skin cells together.

PHARMACOLOGICAL ADVANTAGES

PHYSIOLOGICAL HARMONY

indications for Enriched

Dermatitis / Eczema
Aging Skin
Dry and Tight Skin
Ichthyosis
Volume loss

Lipid Bilayer technology fortifies the skin barrier, restoring its structural integrity, improving its ability to retain moisture, and protecting against external aggressors.

lipid bilayer technology

barrier function & repair

Moisturizers

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Dermrepair

Love DermRepair Face Cream! My skin looks smoother, brighter & more radiant. Absorbs quickly, reduces fine lines & wrinkles, and leaves my skin feeling nourished & hydrated. Perfect addition to my skincare routine! Highly recommend!