DermExcel™

Litaderm Serum: Trial

Name: Litaderm Serum: Trial
Brand: DermExcel™
SKU: DX-LIT05
Price: 15.95 EUR
Availability: InStock

4.9 / 5.0 from 2668 reviews

€15,95

SIZE: 5 mL

Even Skin Tone

Moisturizing

anti-redness

anti-aging

↓ inflammation

A scientifically formulated correction serum that targets various skin concerns, promoting a healthy and radiant complexion. Its powerful blend of multi-tasking active ingredients is supported by peer-reviewed medical literature, ensuring its effectiveness in improving and preventing hyperpigmentation, melasma, redness, acne, rosacea, premature aging, and pigmentation.

The key active ingredients in Litaderm Serum work synergistically to deliver remarkable benefits. Niacinamide, at 10% concentration, enhances skin appearance by reducing hyperpigmentation, promoting even skin tone, and combating inflammation related to acne and rosacea. At 1%, Bakuchiol provides targeted treatment for signs of aging and skin damage, supporting a youthful complexion. With a potent 10% concentration, Azelaic acid reduces hyperpigmentation, redness, and inflammation, contributing to overall healthier skin. Arbutin, comprising 4% of the formula, further aids in correcting hyperpigmentation and promoting a more even complexion.

With its carefully selected ingredients, Litaderm Serum offers a dynamic formulation that comprehensively addresses various skin concerns. Supported by scientific evidence, this serum effectively targets hyperpigmentation, melasma, redness, acne, rosacea, premature aging, and pigmentation. Regularly using Litaderm Serum improves skin tone, texture, and overall radiance, resulting in healthy, radiant, and even-toned skin. Experience the benefits of this targeted approach to achieve a revitalized and rejuvenated appearance.

Niacinamide

Niacinamide offers several benefits for the skin, primarily due to its anti-inflammatory and antioxidant properties. It reduces the redness and inflammation associated with acne, rosacea, and other inflammatory skin conditions. Additionally, niacinamide's ability to improve the skin's barrier function benefits all skin types, particularly those with eczema or mature skin.

Another significant benefit of niacinamide is its role in reducing hyperpigmentation. Studies have shown that it can decrease the transfer of melanin to the epidermis, helping to fade dark spots and even out skin tone.

Niacinamide also plays a role in reducing the visible signs of aging. It has been found to stimulate collagen production and improve skin elasticity, reducing fine lines and wrinkles. Its antioxidant properties further protect the skin from environmental damage, such as pollution and UV radiation, which contribute to premature aging.

The efficacy of niacinamide and its ability to address multiple skin concerns simultaneously has led to its growing popularity in both over-the-counter and prescription skincare formulations.

Physiological Effects

Barrier Function Enhancement: Niacinamide helps strengthen the skin’s barrier function by increasing the production of ceramides, lipids that keep the skin hydrated and protect against environmental damage.
Anti-inflammatory Properties: It has notable anti-inflammatory effects, which are beneficial in reducing redness and inflammation associated with acne, eczema, and other inflammatory skin conditions.
Sebum Regulation: Niacinamide helps regulate sebum production, which controls excess oiliness and can benefit acne-prone skin.
Hyperpigmentation Reduction: It reduces hyperpigmentation by inhibiting melanosome transfer from melanocytes to keratinocytes, leading to an even skin tone.
Anti-aging Effects: Niacinamide helps reduce the appearance of fine lines and wrinkles by boosting collagen production and improving skin elasticity.
Antioxidant Activity: It has antioxidant properties, protecting the skin from oxidative stress and environmental aggressors like UV radiation and pollution.

Role in Managing Dermatological Conditions

Acne and Oily Skin: Niacinamide effectively manages acne and oily skin by regulating sebum and reducing inflammation.
Hyperpigmentation and Melasma: Its ability to reduce melanin transfer benefits it in treating hyperpigmentation and melasma.
Aging Skin: Niacinamide targets wrinkles and loss of firmness.
Skin Barrier Disorders: Niacinamide is beneficial in treating skin barrier disorders like atopic dermatitis and eczema by enhancing barrier function and hydration.
Photodamage and Skin Protection: It helps mitigate the effects of photodamage and provides some degree of protection against environmental damage.

References

Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology.
Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery.
Snaidr, V. A., Damian, D. L., & Halliday, G. M. (2019). Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety. Experimental Dermatology.
Navarrete-Solís, J. et al. (2011). A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Dermatology Research and Practice, 2011.

Azelaic acid

Azelaic acid, a naturally occurring dicarboxylic acid, is an effective ingredient in dermatological treatments, particularly for acne, rosacea, and hyperpigmentation, with antimicrobial and anti-inflammatory properties.

Physiological Effects

Anti-Inflammatory Properties: Azelaic acid reduces inflammation, effectively treating inflammatory skin conditions like acne and rosacea.
Antimicrobial Action: It possesses antimicrobial properties that target acne-causing bacteria (Propionibacterium acnes), helping to reduce acne outbreaks.
Keratolytic Effects: It helps unclog pores and reduce the formation of comedones (black and whiteheads) by normalizing the shedding of skin cells.
Depigmenting Agent: Azelaic acid effectively treats hyperpigmentation disorders, including melasma, as it inhibits tyrosinase, an enzyme involved in melanin production.

Role in Managing Dermatological Conditions

Acne: Azelaic acid inhibits the proliferation of acne-causing bacteria on the skin’s surface, thereby reducing bacterial growth and inflammation. Its antibacterial activity is primarily against Propionibacterium acnes, a key bacterium involved in the development of acne. Furthermore, azelaic acid helps unclog pores and reduce skin cell buildup, effectively treating mild to moderate acne.
Rosacea: Azelaic acid's anti-inflammatory action helps to reduce redness and swelling associated with rosacea. In addition, azelaic acid's ability to reduce keratinization (the process by which skin cells become more fibrous and less flexible) contributes to its effectiveness in this condition.
Pigmentation: Azelaic acid effectively treats melasma and post-inflammatory hyperpigmentation by inhibiting tyrosinase, an enzyme in melanin production. This helps to reduce the formation of excess pigment and can lead to a more even skin tone.

References

Fitton, A., & Goa, K. L. (1991). Azelaic Acid. Drugs.
Gollnick, H., & Schramm, M. (1998). Topical drug treatment in acne. Dermatology.
Passeron, T., et al. (2019). Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a low-dose retinoid. G Ital Dermatol Venereol.
Wolf, J. E., Kerrouche, N., & Arsonnaud, S. (2006). Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. Cutis, 77(4 Suppl), 3-11.
Hollinger, J. C., Angra, K., & Halder, R. M. (2018). Are natural ingredients effective in the management of hyperpigmentation? A systematic review. The Journal of clinical and aesthetic dermatology, 11(2), 28.

Alpha Arbutin

Alpha Arbutin is a derivative of hydroquinone and a biosynthetic active ingredient. Its primary action is inhibiting tyrosinase, a key enzyme involved in the synthesis of melanin, the pigment responsible for skin color. Alpha Arbutin effectively reduces melanin production in the skin by inhibiting tyrosin activity. This gradually lightens hyperpigmented areas, such as age spots, melasma, and scars, resulting in a more even skin tone.

One of the significant advantages of Alpha Arbutin over other skin-lightening agents is its safety profile. Unlike hydroquinone, which has been associated with potential side effects and is restricted in many countries, Alpha Arbutin is considered safe and less irritating to the skin, even at higher concentrations. This makes it a suitable ingredient for all skin types, including sensitive skin.

In addition to its skin-lightening properties, Alpha Arbutin has also shown antioxidant effects, helping to protect the skin from oxidative stress caused by environmental factors like UV radiation and pollution.

Physiological Effects

Melanin Inhibition: Alpha Arbutin works by inhibiting tyrosinase, the enzyme responsible for melanin production in the skin. This action reduces the formation of melanin, leading to a lightening of skin pigmentation.
Even Skin Tone: Regular use of alpha arbutin can lead to a more even skin tone overall, reducing the appearance of age spots and hyperpigmentation.
Reduced Skin Discoloration: It effectively reduces the appearance of dark spots and areas of hyperpigmentation, such as those caused by acne, sun damage, or hormonal changes.
Safer Alternative to Hydroquinone: While structurally similar to hydroquinone, alpha arbutin is a safer option with a lower risk of side effects.

Role in Managing Dermatological Conditions

Hyperpigmentation: Alpha arbutin treats melasma, sun spots, and post-inflammatory hyperpigmentation from acne.
Skin Brightening: Provide a more radiant and uniform skin tone.
Anti-Aging: Reduce the appearance of age-related spots and uneven skin tone.

Bakuchiol

Bakuchiol's mechanism of action is similar to retinol's; it stimulates collagen production and accelerates cell turnover, improving skin texture and tone. It also helps reduce the appearance of fine lines, wrinkles, and hyperpigmentation, making it an effective ingredient in anti-aging skincare products.

One of the key advantages of bakuchiol over traditional retinol is its gentleness on the skin. Retinol is known for potential side effects like dryness, redness, and irritation, particularly in sensitive skin or when used in high concentrations. Bakuchiol, however, is far less irritating. In addition to its anti-aging properties, bakuchiol exhibits antioxidant and anti-inflammatory properties, further contributing to its skin benefits. It helps protect the skin from oxidative stress and can soothe it, reducing redness and inflammation.

Bakuchiol's retinol-like effects and its antioxidant, anti-inflammatory, and antibacterial properties make it an effective ingredient for various skin concerns, especially for those seeking natural alternatives in anti-aging and acne treatment.

Physiological Effects

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Role in Managing Dermatological Conditions

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

References

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.

SHIPPING

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RETURNS

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Litaderm Serum: Trial

€15,95

Aging Skin: Promote cell renewal and improve skin elasticity to target early signs of aging, including fine lines and wrinkles.
Hyperpigmentation: Specifically formulated to improve and prevent hyperpigmentation, helping to reduce the appearance of dark spots, uneven skin tone, and discoloration.
Melasma: Indicated for individuals who have developed patches of facial skin discoloration due to hormonal changes such as pregnancy or birth control use.
Redness and Inflammation: The active ingredients work synergistically to calm inflammation and reduce redness, promoting a more balanced and even-toned complexion.
Skin Damage: Litaderm Serum boosts skin health and supports skin regeneration, Which is indicated for individuals with skin damage, possibly due to environmental factors like sun exposure.
Acne: Reduce inflammation associated with acne, regulate sebum production, and minimize the appearance of blemishes, contributing to clearer and healthier skin.
Rosacea: Reduce the visible signs of rosacea, including redness and enlarged blood vessels.
Dull Lifeless Skin: Reduces melanin production, leading to a more even skin tone.
Overall Skin Health: Nourishes and rejuvenates the skin, promoting a healthier and youthful complexion.

Active ingredients

Niacinamide

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.

Azelaic acid

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.

Alpha Arbutin

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.

Bakuchiol

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.

Full ingredient list

Aqua, Macrogol, Azelaic acid, Nicotinamide, Glycerine, Arbutin, Jojoba Oil, Bakuchiol, Isostearyl Alcohol · Butylene Glycol Cocoate Ethylcellulose, Butylene glycol, Ceteth-20 · Cetyl Alcohol, Glyceryl Stearate, Steareth-20, C12-15 Alkane, Phenylpropanol, Propanediol, Caprylyl Glycol, Tocopherol

Litaderm Serum: Trial

product benefits

Skin barrier enhancement

Stimulate barrier lipids synthesis, improving skin elasticity to ensure a robust defense against environmental damage.

Boost Collagen Production

Restore skin structure by stimulating fibroblast activity and supporting the synthesis of new collagen fibers, improving skin firmness and elasticity.

Anti-Aging

Target aging at the cellular level, increasing skin regeneration, reducing oxidative stress, and enhancing skin firmness and elasticity for a rejuvenated appearance.

Anti-inflammatory

Alleviates skin irritation and redness by targeting inflammatory pathways and markers, offering significant relief for inflamed skin conditions.

Moisturizing

Augment the skin's water-binding capacity, promote barrier repair, and deliver deep, lasting moisture for improved skin comfort and appearance.

Anti-Microbial

Manage microbial activity by inhibiting the growth of pathogenic bacteria, balancing the skin's microbiome, and reducing the risk of infections and inflammation.

Rosacea Relief

Target rosacea symptoms by modulating inflammatory pathways, enhancing skin hydration, and reducing the appearance of erythema and visible blood vessels.

Pigmentation treatment

Diminishes hyperpigmentation by targeting all the pathways involved in melanin synthesis and accelerating the removal of pigmented cells, significantly improving skin tone uniformity and luminosity.

testimonials

Collagen Serum

Best I’ve ever used

Literally nothing has transformed my skin like this serum. I look at high school photos 10 years back and I literally look younger now.

Collagen Serum

This is one of the best products I ever used.

Retinol Serum

I have been using Dermel Health products for a few years and it has absolutely changed my skin. The Retinol Serum has evened out all my fine lines and made my skin look much younger, smooth and soft and even. It has also helped prevent mild breakouts that I used to get. These products really work.

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