Dermal Diagnosis™ | ADR

your dermal diagnosis™ results

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We're thrilled you're taking proactive steps to understand your skin better. Below, you'll find your most recent Dermal Diagnosis™ results. Use this data as a roadmap to achieving healthier skin.

Date	Dermal Diagnosis™	Profile and Treatment Plan

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score	Hydration Score	Pigmentation Score	Inflammation category

Date	Dermal Diagnosis™

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score
Hydration Score
Pigmentation Score
Inflammation category

's Dermal Diagnosis™ Profile

Aging . Dry . Rosacea during pregnancy

Navigating the complexities of your ADR Skin Type during pregnancy, which encompasses aging, dryness, and rosacea, calls for an especially gentle and thoughtful skincare approach. Your skin faces the distinctive challenges of rosacea, including increased proneness to redness, visible blood vessels, and occasional papules or pustules. This is compounded by the typical concerns of aging and exacerbated dryness, making a sensitive and hydrating skincare routine essential.

Your skin's natural lipid production is often insufficient during pregnancy, leading to heightened vulnerability to dehydration and compromised barrier function. Maintaining hydration becomes even more crucial, yet challenging, as your skin struggles to retain moisture. This results in a sensation of tightness and a lackluster appearance due to reduced light reflection. Additionally, the rosacea component introduces a layer of sensitivity, causing your skin to react more intensely to common irritants, allergens, and environmental stressors.

Due to ongoing inflammation and chronic dryness, the signs of aging, such as fine lines and wrinkles, may appear more pronounced. Effectively managing ADR skin during pregnancy involves balancing mitigating these signs of aging and providing the essential hydration and soothing care needed to minimize rosacea symptoms.

When crafting a skincare regimen for ADR skin in pregnancy, it is crucial to select products with safe anti-inflammatory, barrier-repairing, and hydrating ingredients. Ingredients like niacinamide, ceramides, and hyaluronic acid are particularly beneficial, offering soothing, moisturizing, and barrier-strengthening properties. Gentle, mineral-based sunscreens are vital to protect your skin from UV exposure, which can exacerbate rosacea and accelerate aging processes.

It's equally important to avoid known rosacea triggers, which can vary widely but often include hot beverages, spicy foods, alcohol, and certain skincare ingredients. Keeping a diary to track flare-ups related to diet, lifestyle, and product use can be invaluable in identifying and steering clear of personal triggers.

Embracing a skincare routine tailored to the needs of ADR skin during pregnancy requires a commitment to gentle, mindful care, focusing on soothing and hydrating the skin while carefully addressing aging concerns. Consistent and careful skincare practices can enhance your skin's health, reduce rosacea symptoms, and nurture a more resilient and radiant complexion. As with any complex skin condition, especially during pregnancy, consulting with a dermatologist or skincare professional is advisable to personalize your approach and ensure your regimen is effective and safe for your unique needs.

benefits

barriers

goals

YOUR SKIN'S MAIN CHARACTERISTICS

Rosacea

↓ Barrier Function

Dehydration

Aging skin

Benefits of your ADR Pregnancy skin type

Even Skin Tone

Reduced Oiliness

skincare awareness

No Hyperpigmentation The lack of pigmentation issues means that individuals with ADR skin types can enjoy a more consistent and even skin tone.
Reduced Oiliness: You are less likely to experience the sheen and discomfort associated with oily skin types. This can contribute to a matte finish and potentially less clogged pores outside of breakout areas.
Comprehensive Skin Awareness: Managing your skin's diverse needs often results in a heightened understanding and attentiveness to skin health, encouraging proactive and informed skincare choices.

Barriers to your skin health

Rosacea

↓ Barrier Function

Dehydrated Skin

Aging skin

Rosacea Flare-ups: Characterized by redness, visible blood vessels, and sometimes pimples or pustules, rosacea can be triggered by various factors, including certain foods, beverages, temperatures, and stress, making management complex.
Compromised Skin Barrier: Dryness and rosacea contribute to a weakened skin barrier, making the skin more susceptible to irritants, allergens, and environmental damage. This compromised barrier can lead to increased sensitivity and reactivity.
Dehydration: Dry skin inherently struggles to retain moisture, leading to tightness, flakiness, and discomfort. The lack of adequate hydration can exacerbate the appearance of aging signs and rosacea symptoms.
Sensitivity to Skincare Ingredients: Your skin can react adversely to common skincare ingredients, including certain alcohols, fragrances, and exfoliants, making it challenging to find suitable products that do not aggravate the skin.
Increased Visible Aging Signs: The combination of dryness and inflammation can accelerate the appearance of aging signs such as fine lines, wrinkles, and loss of elasticity, particularly in rosacea-affected areas.

your frustrations

Impaired and dehydrated skin barrier.
Premature skin aging.
Rough skin texture with breakouts in certain rosacea types.
Sensitive skin that reacts to various stimuli and products.
Skin prone to redness and inflammation.

your goals

Bright, hydrated, and healthy skin.
No allergic skin reactions.
No redness and inflammation.
Prevention and correction of premature skin aging, including lines and wrinkles.
Smooth skin texture.

Aging . Dry . Rosacea during pregnancy

treatment objectives

Smooth skin texture

Replace dull and dead skin cells with remodelled skin layers. Resurfacing procedures can induce new collagen formation with a more structured pattern.

Deeply Hydrate and Nourish

Advance the skin's hydration capabilities by boosting its capacity to attract and retain moisture at a cellular level. Promote the enhancement of the skin's own hydrating agents, ensuring sustained moisture balance and preventing dryness.

Skin Barrier Restoration

Repair damaged skin barrier and restore barrier function. Boost the protective skin layer by increasing the production of elastin, collagen, ceramides, and lipids.

Prevent & Repair Premature Aging

Protect the skin from factors that accelerate aging, such as UV exposure and pollution, and correct existing signs of aging, like fine lines, wrinkles, and loss of elasticity.

DNA Protection and Repair

Safeguard and repair UV-induced DNA damage, utilizing a blend of UV defense, Retinol, Niacinamide, and antioxidants. This strategy prevents future damage and aids in the repair of existing cellular impairments.

Reduce Inflammation

Alleviate inflammation and redness by restoring equilibrium to the skin's microbiome. Focus on creating a harmonious skin environment that supports healthy bacterial flora, essential for maintaining skin health and preventing breakouts.

include

Anti-inflammatory and anti-microbial agents.
Broad spectrum sunscreen with antioxidants - preventing premature aging and protecting DNA.
Chemical exfoliating ingredients that accelerate cell turnover and reveal new skin cells.
Effective barrier repair agents that restore your skin's natural barrier and prevent premature aging.
Skin-identical medical-grade ingredients that penetrate the skin to activate a biological response.

avoid

Damaging lifestyle habits, e.g., smoking, tanning beds, excessive sun, and sugar consumption.
Toners and foaming cleansers containing soap & sulfates.
Fragrance in skincare products.
Harsh anti-bacterial products that disrupt the skin's natural microbiome.
Irritating plant extracts and essential oils that will trigger adverse reactions.

Aging . Dry . Rosacea during pregnancy

Active Ingredients your skin needs

Azelaic acid

Azelaic acid, a naturally occurring dicarboxylic acid, is an effective ingredient in dermatological treatments, particularly for acne, rosacea, and hyperpigmentation, with antimicrobial and anti-inflammatory properties.

Physiological Effects

Anti-Inflammatory Properties: Azelaic acid reduces inflammation, effectively treating inflammatory skin conditions like acne and rosacea.
Antimicrobial Action: It possesses antimicrobial properties that target acne-causing bacteria (Propionibacterium acnes), helping to reduce acne outbreaks.
Keratolytic Effects: It helps unclog pores and reduce the formation of comedones (black and whiteheads) by normalizing the shedding of skin cells.
Depigmenting Agent: Azelaic acid effectively treats hyperpigmentation disorders, including melasma, as it inhibits tyrosinase, an enzyme involved in melanin production.

Role in Managing Dermatological Conditions

Acne: Azelaic acid inhibits the proliferation of acne-causing bacteria on the skin’s surface, thereby reducing bacterial growth and inflammation. Its antibacterial activity is primarily against Propionibacterium acnes, a key bacterium involved in the development of acne. Furthermore, azelaic acid helps unclog pores and reduce skin cell buildup, effectively treating mild to moderate acne.
Rosacea: Azelaic acid's anti-inflammatory action helps to reduce redness and swelling associated with rosacea. In addition, azelaic acid's ability to reduce keratinization (the process by which skin cells become more fibrous and less flexible) contributes to its effectiveness in this condition.
Pigmentation: Azelaic acid effectively treats melasma and post-inflammatory hyperpigmentation by inhibiting tyrosinase, an enzyme in melanin production. This helps to reduce the formation of excess pigment and can lead to a more even skin tone.

References

Fitton, A., & Goa, K. L. (1991). Azelaic Acid. Drugs.
Gollnick, H., & Schramm, M. (1998). Topical drug treatment in acne. Dermatology.
Passeron, T., et al. (2019). Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a low-dose retinoid. G Ital Dermatol Venereol.
Wolf, J. E., Kerrouche, N., & Arsonnaud, S. (2006). Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. Cutis, 77(4 Suppl), 3-11.
Hollinger, J. C., Angra, K., & Halder, R. M. (2018). Are natural ingredients effective in the management of hyperpigmentation? A systematic review. The Journal of clinical and aesthetic dermatology, 11(2), 28.

Alpha Arbutin

Alpha Arbutin is a derivative of hydroquinone and a biosynthetic active ingredient. Its primary action is inhibiting tyrosinase, a key enzyme involved in the synthesis of melanin, the pigment responsible for skin color. Alpha Arbutin effectively reduces melanin production in the skin by inhibiting tyrosin activity. This gradually lightens hyperpigmented areas, such as age spots, melasma, and scars, resulting in a more even skin tone.

One of the significant advantages of Alpha Arbutin over other skin-lightening agents is its safety profile. Unlike hydroquinone, which has been associated with potential side effects and is restricted in many countries, Alpha Arbutin is considered safe and less irritating to the skin, even at higher concentrations. This makes it a suitable ingredient for all skin types, including sensitive skin.

In addition to its skin-lightening properties, Alpha Arbutin has also shown antioxidant effects, helping to protect the skin from oxidative stress caused by environmental factors like UV radiation and pollution.

Physiological Effects

Melanin Inhibition: Alpha Arbutin works by inhibiting tyrosinase, the enzyme responsible for melanin production in the skin. This action reduces the formation of melanin, leading to a lightening of skin pigmentation.
Even Skin Tone: Regular use of alpha arbutin can lead to a more even skin tone overall, reducing the appearance of age spots and hyperpigmentation.
Reduced Skin Discoloration: It effectively reduces the appearance of dark spots and areas of hyperpigmentation, such as those caused by acne, sun damage, or hormonal changes.
Safer Alternative to Hydroquinone: While structurally similar to hydroquinone, alpha arbutin is a safer option with a lower risk of side effects.

Role in Managing Dermatological Conditions

Hyperpigmentation: Alpha arbutin treats melasma, sun spots, and post-inflammatory hyperpigmentation from acne.
Skin Brightening: Provide a more radiant and uniform skin tone.
Anti-Aging: Reduce the appearance of age-related spots and uneven skin tone.

Salicylic acid

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.

Physiological Effects

Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.