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Mandelic acid
Mandelic acid

Despite its gentler nature, mandelic acid is potent in accelerating cell turnover, aiding in the removal of dead skin cells, and promoting a fresher, more rejuvenated skin appearance.

Mandelic acid's efficacy extends to a wide range of skin concerns. It's particularly beneficial in treating acne, as its antibacterial properties are effective against various strains of bacteria commonly associated with acne development. Moreover, it's known for regulating sebum production and reducing inflammation, further contributing to its acne-fighting capabilities.

Additionally, mandelic acid has shown promise in addressing hyperpigmentation. Its ability to inhibit melanin production helps reduce age spots, sun spots, and uneven skin tones, making it a valuable ingredient in skincare products targeting pigmentation issues. Studies have documented its effectiveness in improving skin texture and reducing the appearance of fine lines and wrinkles, offering a multifaceted approach to skin rejuvenation.

Physiological effects of Mandelic acid
  1. Exfoliation: Mandelic acid gently exfoliates the skin by loosening the bonds between dead skin cells on the surface, promoting their removal and revealing fresh, new skin underneath.
  2. Antibacterial Properties: It possesses antibacterial properties, making it effective against acne-causing bacteria.
  3. Reducing Hyperpigmentation: Mandelic acid is known for its ability to reduce hyperpigmentation, including age spots, sun spots, and marks left by acne, due to its ability to inhibit melanin production.
  4. Anti-aging Effects: It stimulates collagen production, which can help reduce the appearance of fine lines and wrinkles, improving the overall texture of aging skin.
  5. Suitability for Sensitive Skin: Due to its larger molecular size compared to other AHAs, mandelic acid penetrates the skin more slowly and is less likely to cause irritation, making it suitable for sensitive skin types.
Role in managing Dermatological Conditions
  1. Acne Treatment: Its exfoliating and antibacterial properties make mandelic acid effective in treating acne, particularly in those with sensitive skin.
  2. Melasma and Hyperpigmentation: It is beneficial in treating melasma and other forms of hyperpigmentation, lightening dark spots without causing significant irritation.
  3. Aging Skin: Mandelic acid is used in anti-aging skin care products to improve skin texture and diminish signs of aging.
  4. Photo-Aging: It can help to reverse some of the damage caused by UV radiation, such as fine lines and uneven skin tone.
References
  • Briden, M. E. (2004). Noninvasive treatments of acne. In Acne and its Therapy (pp. 341-357). Marcel Dekker.
  • Taylor, M. B. (1999). Summary of mandelic acid for the improvement of skin conditions. Cosmetic Dermatology.
  • Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.