DermExcel™

Excelerate

4.9 / 5.0 from 458 reviews

$12.96

Size:

Strength:

Variant

↓ Sebum

Unclog Pores

Ingrown hair

Anti-Acne

↓ inflammation

A high-potency Salicylic acid treatment available in two strengths – 15% and 30%. This efficacious formulation is designed to systematically counteract acne formation by addressing the critical stages of acne development: comedones, bacteria, and inflammation. It maintains a balance in oil secretion, and its unique keratolytic action accelerates the turnover of skin cells, fostering flaking on the epidermis and inside the pores. This process aids in unclogging pores, a fundamental step in acne management.

The powerful antibacterial properties of Salicylic acid in Excelerate combat acne-causing bacteria, inhibiting their growth and reducing their presence on the skin. This targeted action helps to clear existing acne lesions and prevent the formation of new ones, promoting a clearer complexion. It also down-regulates the inflammatory response associated with acne. Reducing redness and swelling helps soothe the visible signs of inflammation, relieving troubled skin.

Excelerate's dual strengths offer flexibility in treatment options, allowing individuals to choose the appropriate concentration based on their specific needs and skin sensitivity. The 15% strength provides a gentle yet effective approach, while the 30% strength offers a more intensive treatment for stubborn or severe acne.

Excelerate should be used as directed and is recommended for individuals seeking a targeted solution to acne concerns. As with any acne treatment, it is advisable to consult with a healthcare professional or dermatologist to determine the most suitable strength and usage guidelines for your individual skin type and condition.

Salicylic acid | 15%

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.

Physiological Effects

Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

Salicylic acid | 30%

Physiological Effects

Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

USE DURING PREGNANCY

The topical application of Salicylic acid on areas of concern is considered safe during pregnancy.

Most guidelines, including those from the American Academy of Dermatology and various obstetric authorities, suggest that topical Salicylic acid can be used during pregnancy.

Nevertheless, it is always recommended for pregnant women to consult with their healthcare provider before using any medication, including topical treatments.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in USA and Australia, tailored to your shipping address for optimal efficiency.
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When You'll Get It: Expect confident skin soon! Shipping addresses in the USA and Australia will enjoy delivery within 1-4 business days. International orders will receive their orders from 6 to 25 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

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Simple. Effective. Ethical. That's not just our skincare philosophy but our approach to your security too.

Excelerate

$12.96

Acne: Potent Salicylic Acid content, to target moderate to severe acne lesions.
Congested Pores: Excelerate penetrate the pores to dissolve oil and cell debris to unclog pores.
Whiteheads and Blackheads: It effectively treats these comedones by promoting the shedding of cells in the follicular lining.
Folliculitis: A condition characterized by inflammation of hair follicles. By inhibiting the growth of bacteria that contribute to folliculitis, Excelerate alleviate symptoms and reduce the occurrence of this skin condition.
Bacterial Infiltration: Inhibit the growth and reduce bacterial colonization on the skin.
Inflammation: The treatment's anti-inflammatory properties help reduce redness, swelling, and discomfort associated with Acne, Rosacea and other conditions.
Seborrhea: Aid in balancing oil secretion, making it beneficial for managing seborrhea or excessively oily skin.
Keratosis Pilaris: Excelerate promote exfoliation and reduce skin build-up - managing this condition that cause rough, bumpy skin.

Active ingredients

Salicylic acid | 15%

Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

Salicylic acid | 30%

Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

Full ingredient list

Salicylic acid: 15% / Salicylic acid: 30%

Evening

Application time: Evening.
Frequency: Once or twice a month, depending on tolerability and lesion severity.

1. Cleanse

Start with clean and dry skin.
Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2. Apply

Apply on affected areas once or twice a month, depending on tolerability and lesion severity.
Leave on for at least 30 minutes or overnight. If your skin burns beyond tolerability, rinse off.
Avoid sensitive areas like eyelids and lips.

Important Note

Excelerate should be used as directed and is recommended for individuals seeking a targeted solution to acne concerns.
As with any acne treatment, it is advisable to consult with a healthcare professional or dermatologist to determine the most suitable strength and usage guidelines for your skin type and condition.
Always use SPF 30 or greater during the day.

Excelerate

product benefits

Targeted Acne Treatment

Promote cellular turnover, reduce pore congestion, eliminate acne-causing bacteria, and down-regulate inflammation, resulting in a smooth and healthy complexion.

Exfoliate and renew skin cells

Promote cell turnover by accelerating the removal of dead skin cells and stimulating the regeneration of new cells, resulting in a smoother, more radiant complexion.

Unblock clogged pores

Penetrate deeply into the pores to dissolve excess sebum and debris, thereby reducing pore blockage and minimizing the risk of acne formation and enlarged pores.

Anti-inflammatory

Alleviates skin irritation and redness by targeting inflammatory pathways and markers, offering significant relief for inflamed skin conditions.

Excelerate

Mode of action

Exfoliating

SALICYLIC ACID

Salicylic acid works well to balance sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, Salicylic acid penetrates deep into sebum-filled pores.
Salicylic acid works by loosening and breaking apart desmosomes (attachments between cells in the outer layers of the skin). This action encourages the exfoliation of dead and damaged skin and unclogging pores.
Disrupts cellular junctions to exfoliate dead skin cells.

Unclog Pores

SALICYLIC ACID

Salicylic acid is lipophilic, which means it can penetrate oily skin and clogged pores, resulting in deep cleaning.
Decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.

Regulate Sebum (oil)

Salicylic acid works well to balance sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, Salicylic acid penetrates deep into sebum-filled pores.

Microbial Control

It inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis. Therefore, salicylic acid may neutralize the bacteria C. acnes in blemishes.

anti-inflammatory & anti-acne

Salicylic acid reduces sebum secretion.
Salicylic acid has potent anti-inflammatory effects, inhibiting the arachidonic acid cascade.
Salicylic acid reduces inflammation by modulating COX2 gene expression to decrease the formation of pro-inflammatory cytokines.

indications for Excelerate

Facial and Body Acne
Folliculitis
Keratosis Pilaris
Inflammation
Clogged Pores
blackheads
whiteheads

High-potency salicylic acid home chemical peel treatment to target acne, blackheads, and keratosis pilaris.

FDA OTC Drug Monograph

Salicylic acid 3%

The US Food and Drug Administration (FDA) approves salicylic acid in OTC drug products.

In addition to being FDA-approved as a safe and effective acne drug, it is also approved for use in OTC drugs for corn, callus, wart removal, and anti-dandruff drug products.

FDA Category

Indication

CFR 21, 333.310

acne

CFR 21, 358.710 (b)

Seborrheic dermatitis

CFR 21, 358.710 (c)

Psoriasis

salicylic acid

pore clearing action

Sebum (oil) and dead skin cells accumulate inside the pores, causing blackheads and whiteheads.

Salicylic acid has the unique ability to penetrate the pores and to dissolve and extract the oil and dead skin cell plug.

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the stages of acne

Step 1

Regulate sebum (oil) production and secretion

The excretion of lipids by the sebaceous glands is controlled hormonally.
The sebaceous glands are located all over the body but are the largest and most numerous in the face, back, chest, and shoulders.
These glands become more active during puberty because of increased androgens, particularly testosterone, which spurs sebum production.
This imbalance between sebum production and secretion capacity leads to a blockage of sebum in the hair follicle, followed by inflammation.
Hormones continue to affect sebaceous gland activity into adulthood.

Step 2

Prevent and remove content build-up in pores

The first stage of acne is called comedogenesis (formation of comedones).
The exfoliated dead skin cells stick together inside the hair follicle, resulting in a clogged pore or comedone.
This is caused by several factors, including increased amounts of sebum, inflammation of the sides of the hair follicle preventing the release of the exfoliated keratinocytes, and increased cohesion of keratinocytes.
Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris (dead skin cells) in the pores and follicles.

Step 3

Prevent Bacterial Infiltration and infection

The keratinocyte plug and sebum provide excellent food sources for bacteria.
The bacteria invade the comedone and release inflammatory factors that lead to the next stage of acne.
Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Step 4

Down-regulate and prevent inflammation

Inflammation continues with increased redness and pus.
This is clinically detectable as a papule or pustule.
Continued inflammation may lead to so much inflammation that the hair follicle ruptures and the bacteria and debris are released into the dermis.
Salicylic acid suppresses pro-inflammatory cytokine expression.

salicylic acid targets all phases of the acne process

Sebum over-production

Process

The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

______

Targeted treatment

Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores.

Clogged pores

Process

The next step in the development of acne is triggered when the skin's follicles are not exfoliating properly. This means keratin, a protein found within the skin, and sebum clog the follicle.

______

Targeted treatment

Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.
Salicylic acid disrupts cellular junctions to exfoliate dead skin cells.

Bacterial infiltration

Process

When the follicle becomes clogged, a species of bacteria called Cutibacterium acnes (formerly Propionibacterium acnes) accumulates and multiplies in the follicle.

______

Targeted treatment

Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Inflammation

Process

After bacterial infiltration the follicle becomes inflamed, thus leading to pimple formation.

______

Targeted treatment

Salicylic acid suppresses pro-inflammatory cytokine expression.
Salicylic acid inhibits the arachidonic acid cascade.

Sebum over-production

Process

The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

______

Targeted treatment

Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores.

Clogged pores

Process

The next step in the development of acne is triggered when the skin's follicles are not exfoliating properly. This means keratin, a protein found within the skin, and sebum clog the follicle.

______

Targeted treatment

Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.
Salicylic acid disrupts cellular junctions to exfoliate dead skin cells.

Bacterial infiltration

Process

When the follicle becomes clogged, a species of bacteria called Cutibacterium acnes (formerly Propionibacterium acnes) accumulates and multiplies in the follicle.

______

Targeted treatment

Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Inflammation

Process

After bacterial infiltration the follicle becomes inflamed, thus leading to pimple formation.

______

Targeted treatment

Salicylic acid suppresses pro-inflammatory cytokine expression.
Salicylic acid inhibits the arachidonic acid cascade.

Exfoliators

testimonials

Glycolic Gel

Nice texture, makes my skin feel smooth.

Seeing such a difference!

Started my Dermexcel products almost 4 weeks ago, can feel and see such a difference in my skin already! My skin is definitely more hydrated and glowing after such a short time! Yay 🙌🏻

Great product

I really like the Glycolic Gel as part of my facial routine.

Glycolic Gel

Skin feel soft, my skin texture is smooth after this product.

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Excelerate

Excelerate

SALICYLIC ACID

SALICYLIC ACID

Process

Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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