DermExcel™ | Aging.Oily.Allergy Treatment Plan

your dermal diagnosis™ results

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We're thrilled you're taking proactive steps to understand your skin better. Below, you'll find your most recent Dermal Diagnosis™ results. Use this data as a roadmap to achieving healthier skin.

Date	Dermal Diagnosis™	Profile and Treatment Plan

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score	Hydration Score	Pigmentation Score	Inflammation category

Date	Dermal Diagnosis™

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score
Hydration Score
Pigmentation Score
Inflammation category

's Dermal Diagnosis™ Profile

Aging . Oily. Allergy

Your skin profile indicates a likelihood of seborrheic dermatitis, a condition often found in those with oily, aging, and allergy-prone (AOA) skin. This unique combination not only enhances the natural oiliness of your skin but also its sensitivity and susceptibility to allergies. This interplay demands a nuanced approach to maintain skin health and balance.

While contributing to a certain luminosity, the oiliness of your skin may lead to enlarged pores and a persistent glossy sheen. This excess sebum production can also contribute to seborrheic dermatitis, where oily areas of skin become red, itchy, and flaky. Although these oils provide some antioxidant protection, they are often not enough to prevent the signs of aging or to reduce the inflammation characteristic of seborrheic dermatitis.

Your skin's sensitivity and propensity for allergic reactions add further complexity. Symptoms such as redness, scaling, and itchy rashes are typical of seborrheic dermatitis and can exacerbate skin aging by damaging the skin’s barrier function and increasing inflammatory responses.

It is essential to select skincare products that specifically address the needs of AOA skin with a propensity for seborrheic dermatitis. Your regimen should include gentle, anti-inflammatory ingredients that reduce flares and soothe the skin. Products should be free from common irritants and allergens that can trigger reactions and worsen seborrheic dermatitis.

A targeted skincare approach for your AOA Skin Type involves hydrating and calming treatments that respect your skin’s oily nature and sensitivity while supporting its needs to manage symptoms of seborrheic dermatitis. Consistent use of suitable products can aid in repairing and strengthening the skin barrier, improving hydration, and reducing inflammation, ultimately helping to mitigate the risk of premature aging and maintaining healthier skin.

Understanding and embracing the specific needs of your AOA Skin Type with seborrheic dermatitis is crucial. A carefully tailored skincare routine ensures that you address immediate skin concerns and support long-term health and vitality, allowing your skin to retain its resilience and clarity.

benefits

barriers

goals

YOUR SKIN'S MAIN CHARACTERISTICS

Aging Skin

Allergy Prone

↑ Sebum

Large Pores

Benefits of your AOA skin type

Even Skin Tone

hydrated skin

skincare awareness

No Pigmentation: Your skin likely maintains an even tone without the common issues of dark spots or uneven pigmentation. This indicates a balanced distribution of melanin, which, while beneficial for an even complexion, may suggest a need for extra protection against UV radiation due to lower melanin levels.
Natural Hydration: Your oily skin provides a natural layer of hydration, forming a protective barrier against environmental damage. This helps to keep the skin plump and potentially reduces the appearance of fine lines and wrinkles.
Heightened Awareness of Ingredients: Being allergy-prone makes you more vigilant about the ingredients in your skincare products. This heightened awareness can lead to more informed choices, reducing the risk of adverse reactions and promoting skin health.

Barriers to your skin health

Allergy Prone

Aging skin

Oil Management

Inflammation

Allergy prone: Being prone to allergies means your skin may react more sensitively to various external factors, including certain skincare ingredients, environmental allergens, or dietary triggers. This can lead to redness, itching, and irritation, making it crucial to identify and avoid known allergens in your skincare and lifestyle.
Aging Skin: While oily skin may be more resilient to the formation of fine lines and wrinkles, addressing other signs of aging, such as loss of firmness or elasticity, can be complicated by the need to also manage oiliness and enlarged pores.
Oil Management: Finding the balance between reducing excess oil and maintaining skin hydration can be tricky. Over-drying the skin can trigger even more oil production, while too little control can leave the skin looking overly shiny and greasy.
Inflammation: Chronic or occasional inflammation due to allergic reactions can compromise the skin's barrier function, potentially accelerating the aging process and making the skin more vulnerable to external stressors.
Difficulty Finding Suitable Products: The combination of allergy-prone and oiliness can make it challenging to find skincare products that effectively address aging without triggering an allergic reaction or exacerbating oil production.

your frustrations

Oily skin with enlarged pores in certain AOA types.
Premature skin aging.
Sensitive skin that reacts to various stimuli and products.
Skin prone to inflammation.

your goals

No allergic skin reactions.
No Inflammation.
Prevention and correction of premature skin aging including lines and wrinkles.
Regulated sebum (oil) production with clear and minimized pores.

Aging . Oily. Allergy

treatment objectives

Skin Barrier Restoration

Repair damaged skin barrier and restore barrier function. Boost the protective skin layer by increasing the production of elastin, collagen, ceramides, and lipids.

Prevent & Repair Premature Aging

Protect the skin from factors that accelerate aging, such as UV exposure and pollution, and correct existing signs of aging, like fine lines, wrinkles, and loss of elasticity.

Reduce Inflammation

Alleviate inflammation and redness by restoring equilibrium to the skin's microbiome. Focus on creating a harmonious skin environment that supports healthy bacterial flora, essential for maintaining skin health and preventing breakouts.

DNA Protection and Repair

Safeguard and repair UV-induced DNA damage, utilizing a blend of UV defense, Retinol, Niacinamide, and antioxidants. This strategy prevents future damage and aids in the repair of existing cellular impairments.

include

Broad spectrum sunscreen with antioxidants - preventing premature aging and protecting DNA.
Chemical exfoliating ingredients that accelerate cell turnover and reveal new skin cells.
Sebum regulating and pore minimizing ingredients.
Skin identical medical-grade ingredients that penetrate the skin to activate a biological response.

avoid

Damaging lifestyle habits, e.g., smoking, tanning beds, excessive sun, and sugar consumption.
Toners and foaming cleansers containing soap & sulfates.
Fragrance in skincare products.
Harsh anti-bacterial products that disrupt the skin's natural microbiome.
Irritating plant extracts and essential oils that will trigger adverse reactions.

Aging . Oily. Allergy

Active Ingredients your skin needs

Retinoic acid analogue

Retinoic acid, often referred to as tretinoin in its pharmaceutical form, is the active form of Vitamin A. It is widely recognized for its powerful effects in dermatology and skin care, particularly in treating acne and signs of skin aging.

Retinoic acid works at the cellular level to modify gene expression and affect cell growth. In treating acne, it promotes the turnover of skin cells, reducing the likelihood of pore-clogging and helping to clear existing breakouts. Additionally, it decreases the cohesiveness of follicular epithelial cells, further preventing the formation of comedones.

Retinoic acid's ability to stimulate collagen production is a key benefit in anti-aging skincare. This leads to a reduction in fine lines and wrinkles and an improvement in overall skin texture and tone. It also aids skin discoloration and hyperpigmentation by accelerating cell turnover, bringing new skin cells to the surface faster, and shedding pigmented and damaged cells.

Despite its benefits, retinoic acid can irritate the skin, causing side effects like redness, dryness, and peeling, especially during the initial period of use. Its potency means it is generally available by prescription and requires careful monitoring by a healthcare professional.

Hydroxypinacolone Retinoate (HPR) is a newer, esterified form of retinoic acid. Unlike cosmetic retinol, HPR binds directly to the retinoid receptors of the skin cells without needing conversion. This direct binding allows it to deliver similar benefits to retinoic acid, such as stimulating collagen production, improving skin elasticity, and reducing signs of aging, but with a lower risk of irritation.

HPR is considered more gentle and less irritating than traditional retinoic acid while offering comparable benefits. With HPR, everyone has access to the benefits of prescription retinoids without the risk of side effects.

Physiological Effects

Cell Turnover and Renewal: HPR promotes rapid cell turnover, aiding in the exfoliation of dead skin cells and generating new cells.
Skin Texture: Promoting cell renewal improves skin texture and addresses issues like roughness and dullness.
Collagen Production: It stimulates collagen production, which is essential for reducing the appearance of fine lines and wrinkles and improving skin elasticity.
Acne Treatment: Effective in treating acne by unclogging pores and reducing the size of sebaceous glands, it diminishes both inflammatory and non-inflammatory acne lesions.
Pigmentation: It can reduce hyperpigmentation by accelerating the turnover of hyperpigmented skin cells and inhibiting melanin production.
Photoaging: Effective in treating signs of photoaging, reversing some of the damage caused by UV radiation.

Special Benefits

Retinoid Receptor Activity: HPR, an ester of retinoic acid, binds directly to retinoid receptors in the skin, enabling it to work without needing to be converted into retinoic acid.
Lower Irritation: Typically, it causes less irritation than retinoic acid, making it more suitable for sensitive skin types.
Collagen Stimulation and Anti-Aging: Like retinoic acid, HPR helps in stimulating collagen production and has anti-aging properties.
Acne and Hyperpigmentation: It effectively treats acne and reduces hyperpigmentation, often with fewer side effects than retinoic acid.
Stability and Penetration: HPR is more stable and lipid-soluble, so it penetrates the skin more effectively and is less prone to degradation.

References

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., ... & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Fisher, G. J., Wang, Z. Q., Datta, S. C., Varani, J., Kang, S., & Voorhees, J. J. (1996). Pathophysiology of premature skin aging induced by ultraviolet light. New England Journal of Medicine, 337(20), 1419-1428.
Truchuelo, M. T., Jiménez, N., Jaén, P. (2018). Assessment of the efficacy of a new complex-based retinoic acid and retinol in a 3-month study using objective methods and skin biomarker analysis. Journal of Cosmetic Dermatology, 17(3), 347-354.
Mukherjee, S., et al. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging.
Randhawa, M., et al. (2015). Hydroxypinacolone retinoate: a new retinoid and its use in dermatology. Skin Therapy Letter.

Azelaic acid

Azelaic acid, a naturally occurring dicarboxylic acid, is an effective ingredient in dermatological treatments, particularly for acne, rosacea, and hyperpigmentation, with antimicrobial and anti-inflammatory properties.

Physiological Effects

Anti-Inflammatory Properties: Azelaic acid reduces inflammation, effectively treating inflammatory skin conditions like acne and rosacea.
Antimicrobial Action: It possesses antimicrobial properties that target acne-causing bacteria (Propionibacterium acnes), helping to reduce acne outbreaks.
Keratolytic Effects: It helps unclog pores and reduce the formation of comedones (black and whiteheads) by normalizing the shedding of skin cells.
Depigmenting Agent: Azelaic acid effectively treats hyperpigmentation disorders, including melasma, as it inhibits tyrosinase, an enzyme involved in melanin production.

Role in Managing Dermatological Conditions

Acne: Azelaic acid inhibits the proliferation of acne-causing bacteria on the skin’s surface, thereby reducing bacterial growth and inflammation. Its antibacterial activity is primarily against Propionibacterium acnes, a key bacterium involved in the development of acne. Furthermore, azelaic acid helps unclog pores and reduce skin cell buildup, effectively treating mild to moderate acne.
Rosacea: Azelaic acid's anti-inflammatory action helps to reduce redness and swelling associated with rosacea. In addition, azelaic acid's ability to reduce keratinization (the process by which skin cells become more fibrous and less flexible) contributes to its effectiveness in this condition.
Pigmentation: Azelaic acid effectively treats melasma and post-inflammatory hyperpigmentation by inhibiting tyrosinase, an enzyme in melanin production. This helps to reduce the formation of excess pigment and can lead to a more even skin tone.

References

Fitton, A., & Goa, K. L. (1991). Azelaic Acid. Drugs.
Gollnick, H., & Schramm, M. (1998). Topical drug treatment in acne. Dermatology.
Passeron, T., et al. (2019). Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a low-dose retinoid. G Ital Dermatol Venereol.
Wolf, J. E., Kerrouche, N., & Arsonnaud, S. (2006). Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. Cutis, 77(4 Suppl), 3-11.
Hollinger, J. C., Angra, K., & Halder, R. M. (2018). Are natural ingredients effective in the management of hyperpigmentation? A systematic review. The Journal of clinical and aesthetic dermatology, 11(2), 28.

Bakuchiol

Bakuchiol's mechanism of action is similar to retinol's; it stimulates collagen production and accelerates cell turnover, improving skin texture and tone. It also helps reduce the appearance of fine lines, wrinkles, and hyperpigmentation, making it an effective ingredient in anti-aging skincare products.

One of the key advantages of bakuchiol over traditional retinol is its gentleness on the skin. Retinol is known for potential side effects like dryness, redness, and irritation, particularly in sensitive skin or when used in high concentrations. Bakuchiol, however, is far less irritating. In addition to its anti-aging properties, bakuchiol exhibits antioxidant and anti-inflammatory properties, further contributing to its skin benefits. It helps protect the skin from oxidative stress and can soothe it, reducing redness and inflammation.

Bakuchiol's retinol-like effects and its antioxidant, anti-inflammatory, and antibacterial properties make it an effective ingredient for various skin concerns, especially for those seeking natural alternatives in anti-aging and acne treatment.

Physiological Effects

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Role in Managing Dermatological Conditions

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

References

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.