Dermal Diagnosis™ | ADPR

your dermal diagnosis™ results

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We're thrilled you're taking proactive steps to understand your skin better. Below, you'll find your most recent Dermal Diagnosis™ results. Use this data as a roadmap to achieving healthier skin.

Date	Dermal Diagnosis™	Profile and Treatment Plan

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score	Hydration Score	Pigmentation Score	Inflammation category

Date	Dermal Diagnosis™

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score
Hydration Score
Pigmentation Score
Inflammation category

's Dermal Diagnosis™ Profile

Aging . Dry . Pigmentation . Rosacea

Navigating the complexities of your ADPR Skin Type during pregnancy, which combines dryness, sensitivity, pigmentation issues, and visible signs of aging, requires a tailored and sensitive skincare approach. Pregnancy can amplify these challenges, making it essential to adopt a scientifically proven regimen that's safe during this special time.

Your skin's limited natural oil production, crucial for maintaining hydration and defending against external stressors, becomes even more pronounced during pregnancy. This shortfall can leave your complexion feeling tight and looking dull, as it struggles to reflect light properly.

You may often experience a flushed appearance with redness and visible tiny blood vessels, which is common in rosacea. In more severe cases, you might see breakouts or thickened skin. Eye discomfort, such as dryness or irritation around the eyelids, can also be prevalent. These symptoms cause immediate discomfort and contribute to the accelerated development of fine lines and wrinkles due to ongoing inflammation.

The weakened barrier of ADPR skin, particularly during pregnancy, makes it more susceptible to irritants and allergens while struggling to retain essential moisture. This vulnerability can complicate the search for suitable skincare products, as many can exacerbate your symptoms rather than alleviate them.

However, a dedicated regimen tailored to pregnancy can significantly improve your skin's ability to hold onto moisture, reduce sensitivity and redness, and gradually diminish the signs of aging and pigmentation. This regimen should focus on hydrating, soothing, and barrier-repairing ingredients that are safe during pregnancy. Products containing niacinamide, ceramides, and gentle, non-irritating formulations can be particularly beneficial. Additionally, mineral-based sunscreens are essential to protect your skin from UV rays, which can aggravate rosacea and accelerate signs of aging.

Embracing a skincare routine that carefully addresses the unique needs of your ADPR skin during pregnancy can enhance your skin’s resilience, leading to a healthier and more comfortable complexion. As with any skincare during pregnancy, consulting with a dermatologist to ensure safety and effectiveness is highly recommended.

benefits

barriers

goals

YOUR SKIN'S MAIN CHARACTERISTICS

Rosacea

Dehydration

Pigmentation

Aging skin

Benefits of your ADPR Pregnancy skin type

Reduced Oiliness

skincare awareness

Reduced Oiliness: You are less likely to experience the sheen and discomfort associated with oily skin types. This can contribute to a matte finish and potentially less clogged pores outside of breakout areas.
Comprehensive Skin Awareness: Managing your skin's diverse needs often results in a heightened understanding and attentiveness to skin health, encouraging proactive and informed skincare choices.

Barriers to your skin health

Rosacea

Dehydrated Skin

Pigmentation

Aging skin

Rosacea Flare-ups: Characterized by redness, visible blood vessels, and sometimes pimples or pustules, rosacea can be triggered by various factors, including certain foods, beverages, temperatures, and stress, making management complex.
Compromised Skin Barrier: Dryness and rosacea contribute to a weakened skin barrier, making the skin more susceptible to irritants, allergens, and environmental damage. This compromised barrier can lead to increased sensitivity and reactivity.
Dehydration: Dry skin inherently struggles to retain moisture, leading to tightness, flakiness, and discomfort. The lack of adequate hydration can exacerbate the appearance of aging signs and rosacea symptoms.
Sensitivity to Skincare Ingredients: Your skin can react adversely to common skincare ingredients, including certain alcohols, fragrances, and exfoliants, making it challenging to find suitable products that do not aggravate the skin.
Hyperpigmentation: Issues such as uneven skin tone, dark spots, and melasma are prominent and require consistent management and treatment.
Increased Visible Aging Signs: The combination of dryness and inflammation can accelerate the appearance of aging signs such as fine lines, wrinkles, and loss of elasticity, particularly in rosacea-affected areas.

your frustrations

Impaired and dehydrated skin barrier.
Rough skin texture with breakouts in certain rosacea types.
Sensitive skin that reacts to various stimuli and products.
Skin prone to redness and inflammation.
Uneven skin tone with dark spots or patches.

your goals

Bright; hydrated and healthy skin.
No redness and inflammation.
Prevention and correction of premature skin aging including lines and wrinkles.
Protected; smooth and healed skin barrier.
Radiant skin with an even skin tone.

Aging . Dry . Pigmentation . Rosacea

treatment objectives

Inhibit hyperpigmentation

Inhibit the pathways in the hyperpigmentation process to stop the stimulation, production and transfer of melanin (pigment cells).

Deeply Hydrate and Nourish

Advance the skin's hydration capabilities by boosting its capacity to attract and retain moisture at a cellular level. Promote the enhancement of the skin's own hydrating agents, ensuring sustained moisture balance and preventing dryness.

Prevent & Repair Premature Aging

Protect the skin from factors that accelerate aging, such as UV exposure and pollution, and correct existing signs of aging, like fine lines, wrinkles, and loss of elasticity.

Skin Barrier Restoration

Repair damaged skin barrier and restore barrier function. Boost the protective skin layer by increasing the production of elastin, collagen, ceramides, and lipids.

Reduce Inflammation

Alleviate inflammation and redness by restoring equilibrium to the skin's microbiome. Focus on creating a harmonious skin environment that supports healthy bacterial flora, essential for maintaining skin health and preventing breakouts.

DNA Protection and Repair

Safeguard and repair UV-induced DNA damage, utilizing a blend of UV defense, Retinol, Niacinamide, and antioxidants. This strategy prevents future damage and aids in the repair of existing cellular impairments.

include

Anti-inflammatory, anti-microbial and pigmentation-disruptive ingredients.
Broad spectrum sunscreen with antioxidants - preventing premature aging and protecting DNA.
Effective barrier repair agents restore your skin's natural barrier and prevent premature aging.
Hypoallergenic and pigmentation-disruptive ingredients.
Skin-identical medical-grade ingredients that penetrate the skin to activate a biological response.

avoid

Damaging lifestyle habits, e.g., smoking, tanning beds, excessive sun, and sugar consumption.
Toners and foaming cleansers containing soap & sulfates.
Fragrance in skincare products.
Harsh anti-bacterial products that disrupt the skin's natural microbiome.
Irritating plant extracts and essential oils that will trigger adverse reactions.

Aging . Dry . Pigmentation . Rosacea

Active Ingredients your skin needs

Azelaic acid

Azelaic acid, a naturally occurring dicarboxylic acid, is an effective ingredient in dermatological treatments, particularly for acne, rosacea, and hyperpigmentation, with antimicrobial and anti-inflammatory properties.

Physiological Effects

Anti-Inflammatory Properties: Azelaic acid reduces inflammation, effectively treating inflammatory skin conditions like acne and rosacea.
Antimicrobial Action: It possesses antimicrobial properties that target acne-causing bacteria (Propionibacterium acnes), helping to reduce acne outbreaks.
Keratolytic Effects: It helps unclog pores and reduce the formation of comedones (black and whiteheads) by normalizing the shedding of skin cells.
Depigmenting Agent: Azelaic acid effectively treats hyperpigmentation disorders, including melasma, as it inhibits tyrosinase, an enzyme involved in melanin production.

Role in Managing Dermatological Conditions

Acne: Azelaic acid inhibits the proliferation of acne-causing bacteria on the skin’s surface, thereby reducing bacterial growth and inflammation. Its antibacterial activity is primarily against Propionibacterium acnes, a key bacterium involved in the development of acne. Furthermore, azelaic acid helps unclog pores and reduce skin cell buildup, effectively treating mild to moderate acne.
Rosacea: Azelaic acid's anti-inflammatory action helps to reduce redness and swelling associated with rosacea. In addition, azelaic acid's ability to reduce keratinization (the process by which skin cells become more fibrous and less flexible) contributes to its effectiveness in this condition.
Pigmentation: Azelaic acid effectively treats melasma and post-inflammatory hyperpigmentation by inhibiting tyrosinase, an enzyme in melanin production. This helps to reduce the formation of excess pigment and can lead to a more even skin tone.

References

Fitton, A., & Goa, K. L. (1991). Azelaic Acid. Drugs.
Gollnick, H., & Schramm, M. (1998). Topical drug treatment in acne. Dermatology.
Passeron, T., et al. (2019). Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a low-dose retinoid. G Ital Dermatol Venereol.
Wolf, J. E., Kerrouche, N., & Arsonnaud, S. (2006). Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. Cutis, 77(4 Suppl), 3-11.
Hollinger, J. C., Angra, K., & Halder, R. M. (2018). Are natural ingredients effective in the management of hyperpigmentation? A systematic review. The Journal of clinical and aesthetic dermatology, 11(2), 28.

Alpha Arbutin

Alpha Arbutin is a derivative of hydroquinone and a biosynthetic active ingredient. Its primary action is inhibiting tyrosinase, a key enzyme involved in the synthesis of melanin, the pigment responsible for skin color. Alpha Arbutin effectively reduces melanin production in the skin by inhibiting tyrosin activity. This gradually lightens hyperpigmented areas, such as age spots, melasma, and scars, resulting in a more even skin tone.

One of the significant advantages of Alpha Arbutin over other skin-lightening agents is its safety profile. Unlike hydroquinone, which has been associated with potential side effects and is restricted in many countries, Alpha Arbutin is considered safe and less irritating to the skin, even at higher concentrations. This makes it a suitable ingredient for all skin types, including sensitive skin.

In addition to its skin-lightening properties, Alpha Arbutin has also shown antioxidant effects, helping to protect the skin from oxidative stress caused by environmental factors like UV radiation and pollution.

Physiological Effects

Melanin Inhibition: Alpha Arbutin works by inhibiting tyrosinase, the enzyme responsible for melanin production in the skin. This action reduces the formation of melanin, leading to a lightening of skin pigmentation.
Even Skin Tone: Regular use of alpha arbutin can lead to a more even skin tone overall, reducing the appearance of age spots and hyperpigmentation.
Reduced Skin Discoloration: It effectively reduces the appearance of dark spots and areas of hyperpigmentation, such as those caused by acne, sun damage, or hormonal changes.
Safer Alternative to Hydroquinone: While structurally similar to hydroquinone, alpha arbutin is a safer option with a lower risk of side effects.

Role in Managing Dermatological Conditions

Hyperpigmentation: Alpha arbutin treats melasma, sun spots, and post-inflammatory hyperpigmentation from acne.
Skin Brightening: Provide a more radiant and uniform skin tone.
Anti-Aging: Reduce the appearance of age-related spots and uneven skin tone.

Bakuchiol

Bakuchiol's mechanism of action is similar to retinol's; it stimulates collagen production and accelerates cell turnover, improving skin texture and tone. It also helps reduce the appearance of fine lines, wrinkles, and hyperpigmentation, making it an effective ingredient in anti-aging skincare products.

One of the key advantages of bakuchiol over traditional retinol is its gentleness on the skin. Retinol is known for potential side effects like dryness, redness, and irritation, particularly in sensitive skin or when used in high concentrations. Bakuchiol, however, is far less irritating. In addition to its anti-aging properties, bakuchiol exhibits antioxidant and anti-inflammatory properties, further contributing to its skin benefits. It helps protect the skin from oxidative stress and can soothe it, reducing redness and inflammation.

Bakuchiol's retinol-like effects and its antioxidant, anti-inflammatory, and antibacterial properties make it an effective ingredient for various skin concerns, especially for those seeking natural alternatives in anti-aging and acne treatment.

Physiological Effects

Retinol-like Function: Bakuchiol mimics the actions of retinol, stimulating collagen production. This helps reduce the appearance of fine lines and wrinkles and improves skin elasticity.
Antioxidant Properties: It offers antioxidant benefits, protecting the skin from oxidative stress and damage caused by environmental factors like UV radiation.
Anti-inflammatory Effects: Bakuchiol has anti-inflammatory properties, which can help soothe the skin and reduce redness and irritation.
Improved Skin Tone and Texture: Regular use of bakuchiol can improve skin tone and texture, making it smoother and more even.
Acne Management: Bakuchiol's antibacterial properties and ability to regulate sebum production make it effective in managing acne.

Role in Managing Dermatological Conditions

Aging Skin: Bakuchiol is popular in anti-aging skincare because it stimulates collagen production and reduces signs of aging.
Sensitive Skin: As a gentler alternative to retinol, it is suitable for sensitive skin types that cannot tolerate traditional retinoids.
Acne-Prone Skin: Its antibacterial and anti-inflammatory properties are beneficial in acne treatments.
Hyperpigmentation: Bakuchiol can help treat hyperpigmentation, enhance skin radiance, and reduce dark spots.

References

Chaudhuri, R. K., & Bojanowski, K. (2014). Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science.
Dhaliwal, S., et al. (2019). Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology.
Sivamani, R. K., et al. (2019). Clinical efficacy of a bakuchiol, niacinamide and zinc pyrithione formulation in facial sebum control and mild acne. Journal of Cosmetic Dermatology.