DermExcel™ | Aging.Oily.Breakouts Treatment Pack

your dermal diagnosis™ results

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We're thrilled you're taking proactive steps to understand your skin better. Below, you'll find your most recent Dermal Diagnosis™ results. Use this data as a roadmap to achieving healthier skin.

Date	Dermal Diagnosis™	Profile and Treatment Plan

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score	Hydration Score	Pigmentation Score	Inflammation category

Date	Dermal Diagnosis™

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score
Hydration Score
Pigmentation Score
Inflammation category

's Dermal Diagnosis™ Profile

Aging . Oily . Breakouts

Your AOB Skin Type, marked by Aging, Oiliness, and Breakouts, navigates the often challenging waters of managing excess oil and acne while addressing the natural aging process. This skin type is indeed common, combining the vitality of oily skin with the complexities of breakouts and the wisdom of maturing skin.

The inflammation characteristic of acne breakouts, presenting as redness, pimples, and possibly more severe acne, plays a significant role in your skin's health. This inflammation not only causes immediate concern in the form of visible blemishes but can also accelerate the aging process, contributing to fine lines, wrinkles, and changes in skin texture over time.

The oiliness can lead to a glossy appearance and enlarged pores, hallmarks of your skin type that require diligent care. Congested pores, characterized by blackheads and whiteheads, signal the need for a skincare regimen that balances effective cleansing with maintaining the skin's natural hydration.

Navigating AOB skin involves a multifaceted approach: incorporating anti-inflammatory and antioxidant-rich ingredients to soothe and protect the skin, employing non-comedogenic products that hydrate without clogging pores, and integrating targeted treatments to simultaneously address breakouts and signs of aging.

Your skincare journey with AOB Skin Type is about achieving balance—reducing oiliness and clearing breakouts while gently supporting your skin through the aging process. With consistent care and the right products, your skin can embrace clarity, vitality, and a youthful appearance, reflecting your dedication to well-being.

benefits

barriers

goals

YOUR SKIN'S MAIN CHARACTERISTICS

Acne Breakouts

↑ Sebum

Aging Skin

Clogged Pores

Benefits of your AOB skin type

hydrated skin

Even Skin Tone

protective barrier

Natural Hydration: Your oily skin provides a natural layer of hydration, forming a protective barrier against environmental damage. This helps to keep the skin plump and potentially reduces the appearance of fine lines and wrinkles.
Even Skin Tone: The lack of hyperpigmentation issues means that you enjoy a more consistent and even skin tone.
Protective Barrier: The excess sebum can act as a protective barrier against environmental aggressors, potentially reducing the impact of pollutants and other irritants.

Barriers to your skin health

Acne Breakouts

Oil Management

Aging skin

Inflammation

Breakouts and Acne: The propensity for clogged pores can lead to blackheads, whiteheads, and more severe forms of acne, which can be challenging to manage and may lead to scarring or post-inflammatory hyperpigmentation.
Sebum Control: Controlling excess oil and shine, especially in the T-zone area, can be a constant struggle, affecting the skin's overall appearance.
Aging Skin: While oily skin may be more resilient to the formation of fine lines and wrinkles, addressing other signs of aging, such as loss of firmness or elasticity, can be complicated by the need to also manage oiliness and enlarged pores.
Inflammation: The inflammation associated with breakouts can accelerate skin aging, contribute to wrinkles, and cause skin to lose elasticity over time.
Enlarged pores: The excess oil production can lead to enlarged pores and increase the likelihood of blackheads, whiteheads, and acne, which can be challenging to manage alongside aging skin concerns.
Product Selection: Identifying skincare and makeup products that address oiliness, prevent and treat breakouts, and tackle aging signs without irritating can be a complex task.

your frustrations

Breakouts, clogged pores, and inflamed skin.
Oily and shiny skin with enlarged pores.
Premature skin aging.
Sensitive skin that reacts to various stimuli and products.

your goals

Smooth and healthy skin with no breakouts or inflammation.
Comfortable skin sensations with no itching or other skin discomforts.
Prevention and correction of premature skin aging, including lines and wrinkles.
Regulated sebum (oil) production with clear and minimized pores.

Aging . Oily . Breakouts

treatment objectives

Smooth skin texture

Replace dull and dead skin cells with remodelled skin layers. Resurfacing procedures can induce new collagen formation with a more structured pattern.

Regulate sebum

Balance oil production to minimize shine and reduce the likelihood of congestion and breakouts without stripping the skin of its natural oils.

Unclog pores

Dissolve and extract cellular debris and prevent skin cells from clumping together in pores to ensure that the pores remain clear and free from blockages, which can lead to breakouts.

Clear Acne Breakouts

Reduce and eliminate breakouts by down-regulating the inflammatory response and balancing the skin microbiome.

Prevent & Repair Premature Aging

Protect the skin from factors that accelerate aging, such as UV exposure and pollution, and correct existing signs of aging, like fine lines, wrinkles, and loss of elasticity.

DNA Protection and Repair

Safeguard and repair UV-induced DNA damage, utilizing a blend of UV defense, Retinol, Niacinamide, and antioxidants. This strategy prevents future damage and aids in the repair of existing cellular impairments.

include

Anti-inflammatory and anti-microbial agents.
Broad spectrum sunscreen with antioxidants - preventing premature aging and protecting DNA.
Pigmentation-disrupting ingredients and chemical exfoliating ingredients that accelerate cell turnover and reveal new skin cells.
Sebum regulating and pore minimizing ingredients.
Skin identical medical-grade ingredients that penetrate the skin to activate a biological response.

avoid

Damaging lifestyle habits, e.g., smoking, tanning beds, excessive sun, and sugar consumption.
Toners and foaming cleansers containing soap & sulfates.
Fragrance in skincare products.
Harsh anti-bacterial products that disrupt the skin's natural microbiome.
Irritating plant extracts and essential oils that will trigger adverse reactions.

Aging . Oily . Breakouts

Active Ingredients your skin needs

Retinoic acid analogue

Retinoic acid, often referred to as tretinoin in its pharmaceutical form, is the active form of Vitamin A. It is widely recognized for its powerful effects in dermatology and skin care, particularly in treating acne and signs of skin aging.

Retinoic acid works at the cellular level to modify gene expression and affect cell growth. In treating acne, it promotes the turnover of skin cells, reducing the likelihood of pore-clogging and helping to clear existing breakouts. Additionally, it decreases the cohesiveness of follicular epithelial cells, further preventing the formation of comedones.

Retinoic acid's ability to stimulate collagen production is a key benefit in anti-aging skincare. This leads to a reduction in fine lines and wrinkles and an improvement in overall skin texture and tone. It also aids skin discoloration and hyperpigmentation by accelerating cell turnover, bringing new skin cells to the surface faster, and shedding pigmented and damaged cells.

Despite its benefits, retinoic acid can irritate the skin, causing side effects like redness, dryness, and peeling, especially during the initial period of use. Its potency means it is generally available by prescription and requires careful monitoring by a healthcare professional.

Hydroxypinacolone Retinoate (HPR) is a newer, esterified form of retinoic acid. Unlike cosmetic retinol, HPR binds directly to the retinoid receptors of the skin cells without needing conversion. This direct binding allows it to deliver similar benefits to retinoic acid, such as stimulating collagen production, improving skin elasticity, and reducing signs of aging, but with a lower risk of irritation.

HPR is considered more gentle and less irritating than traditional retinoic acid while offering comparable benefits. With HPR, everyone has access to the benefits of prescription retinoids without the risk of side effects.

Physiological Effects

Cell Turnover and Renewal: HPR promotes rapid cell turnover, aiding in the exfoliation of dead skin cells and generating new cells.
Skin Texture: Promoting cell renewal improves skin texture and addresses issues like roughness and dullness.
Collagen Production: It stimulates collagen production, which is essential for reducing the appearance of fine lines and wrinkles and improving skin elasticity.
Acne Treatment: Effective in treating acne by unclogging pores and reducing the size of sebaceous glands, it diminishes both inflammatory and non-inflammatory acne lesions.
Pigmentation: It can reduce hyperpigmentation by accelerating the turnover of hyperpigmented skin cells and inhibiting melanin production.
Photoaging: Effective in treating signs of photoaging, reversing some of the damage caused by UV radiation.

Special Benefits

Retinoid Receptor Activity: HPR, an ester of retinoic acid, binds directly to retinoid receptors in the skin, enabling it to work without needing to be converted into retinoic acid.
Lower Irritation: Typically, it causes less irritation than retinoic acid, making it more suitable for sensitive skin types.
Collagen Stimulation and Anti-Aging: Like retinoic acid, HPR helps in stimulating collagen production and has anti-aging properties.
Acne and Hyperpigmentation: It effectively treats acne and reduces hyperpigmentation, often with fewer side effects than retinoic acid.
Stability and Penetration: HPR is more stable and lipid-soluble, so it penetrates the skin more effectively and is less prone to degradation.

References

Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., ... & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
Fisher, G. J., Wang, Z. Q., Datta, S. C., Varani, J., Kang, S., & Voorhees, J. J. (1996). Pathophysiology of premature skin aging induced by ultraviolet light. New England Journal of Medicine, 337(20), 1419-1428.
Truchuelo, M. T., Jiménez, N., Jaén, P. (2018). Assessment of the efficacy of a new complex-based retinoic acid and retinol in a 3-month study using objective methods and skin biomarker analysis. Journal of Cosmetic Dermatology, 17(3), 347-354.
Mukherjee, S., et al. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging.
Randhawa, M., et al. (2015). Hydroxypinacolone retinoate: a new retinoid and its use in dermatology. Skin Therapy Letter.

Aloe Vera

Aloe vera is well-regarded for its medicinal applications and has been a staple in skincare and health for centuries. It’s rich in vitamins, enzymes, minerals, and amino acids, contributing to its many skin benefits.

Aloe vera contains polysaccharides, which are crucial in its moisturizing and anti-inflammatory properties. These polysaccharides help bind moisture to the skin, making aloe vera an excellent hydrating agent for dry and damaged skin.

One of the key benefits of aloe vera is its soothing and healing properties, particularly beneficial for burns, abrasions, and skin irritations. It has been shown to accelerate the healing of minor burns and reduce skin inflammation. Various studies have supported its effectiveness in treating first- and second-degree burns, highlighting its role in enhancing collagen synthesis and skin regeneration.

Aloe vera's anti-inflammatory properties are attributed to compounds like glycoproteins and polysaccharides. These compounds help reduce pain and swelling associated with skin irritations and wounds. Aloe vera also contains aloin and emodin, which provide analgesic, antibacterial, and antiviral properties, further extending its therapeutic potential.

Aloe Vera has numerous physiological effects on the skin due to its rich composition of vitamins, enzymes, minerals, and amino acids. The presence of antioxidants such as vitamins C and E, along with beta-carotene, contributes to its anti-aging benefits, helping to improve skin firmness and keep the skin hydrated.

Physiological Effects

Moisturizing and Hydrating: Aloe Vera enhances skin hydration, making it effective for dry and dehydrated skin. Its mucopolysaccharides help to bind moisture into the skin.
Wound Healing: It accelerates wound healing by enhancing collagen synthesis and cross-linking. This effect is particularly useful in healing burns, abrasions, and cuts.
Anti-inflammatory Properties: Aloe Vera contains compounds like aloin and anthraquinones that have anti-inflammatory properties, making it beneficial in reducing skin inflammation.
Antimicrobial Activity: It possesses antimicrobial properties, which help in preventing infections in wounds and burns.
Antioxidant Properties: The presence of vitamins C and E and beta-carotene provides it with antioxidant properties, which can help protect the skin from free radical damage.
Soothing Effect: Aloe Vera is known for its soothing effects on the skin, particularly in conditions like sunburn.

Role in Managing Dermatological Conditions

Burns and Wound Care: Aloe Vera's wound-healing and soothing properties make it effective in treating burns, including sunburns and minor skin abrasions.
Acne Treatment: Due to its antimicrobial and anti-inflammatory properties, it can help treat acne.
Eczema and Psoriasis: Its moisturizing, anti-inflammatory, and soothing properties are beneficial in managing symptoms of eczema and psoriasis.
Aging Skin: Aloe Vera's antioxidant properties and ability to improve collagen production can help reduce the signs of aging.
Skin Hydration: It's a common ingredient in moisturizers and other skin care products for its hydrating properties.

References

Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology.
Maenthaisong, R., Chaiyakunapruk, N., Niruntraporn, S., & Kongkaew, C. (2007). The efficacy of aloe vera used for burn wound healing: A systematic review. Burns.
Rajeswari, R., Umadevi, M., Rahale, C. S., Pushpa, R., Selvavenkadesh, S., Kumar, K. S., & Bhowmik, D. (2012). Aloe vera: The miracle plant its medicinal and traditional uses in India. Journal of Pharmacognosy and Phytochemistry.

Niacinamide

Niacinamide offers several benefits for the skin, primarily due to its anti-inflammatory and antioxidant properties. It reduces the redness and inflammation associated with acne, rosacea, and other inflammatory skin conditions. Additionally, niacinamide's ability to improve the skin's barrier function benefits all skin types, particularly those with eczema or mature skin.

Another significant benefit of niacinamide is its role in reducing hyperpigmentation. Studies have shown that it can decrease the transfer of melanin to the epidermis, helping to fade dark spots and even out skin tone.

Niacinamide also plays a role in reducing the visible signs of aging. It has been found to stimulate collagen production and improve skin elasticity, reducing fine lines and wrinkles. Its antioxidant properties further protect the skin from environmental damage, such as pollution and UV radiation, which contribute to premature aging.

The efficacy of niacinamide and its ability to address multiple skin concerns simultaneously has led to its growing popularity in both over-the-counter and prescription skincare formulations.

Physiological Effects

Barrier Function Enhancement: Niacinamide helps strengthen the skin’s barrier function by increasing the production of ceramides, lipids that keep the skin hydrated and protect against environmental damage.
Anti-inflammatory Properties: It has notable anti-inflammatory effects, which are beneficial in reducing redness and inflammation associated with acne, eczema, and other inflammatory skin conditions.
Sebum Regulation: Niacinamide helps regulate sebum production, which controls excess oiliness and can benefit acne-prone skin.
Hyperpigmentation Reduction: It reduces hyperpigmentation by inhibiting melanosome transfer from melanocytes to keratinocytes, leading to an even skin tone.
Anti-aging Effects: Niacinamide helps reduce the appearance of fine lines and wrinkles by boosting collagen production and improving skin elasticity.
Antioxidant Activity: It has antioxidant properties, protecting the skin from oxidative stress and environmental aggressors like UV radiation and pollution.

Role in Managing Dermatological Conditions

Acne and Oily Skin: Niacinamide effectively manages acne and oily skin by regulating sebum and reducing inflammation.
Hyperpigmentation and Melasma: Its ability to reduce melanin transfer benefits it in treating hyperpigmentation and melasma.
Aging Skin: Niacinamide targets wrinkles and loss of firmness.
Skin Barrier Disorders: Niacinamide is beneficial in treating skin barrier disorders like atopic dermatitis and eczema by enhancing barrier function and hydration.
Photodamage and Skin Protection: It helps mitigate the effects of photodamage and provides some degree of protection against environmental damage.

References

Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology.
Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery.
Snaidr, V. A., Damian, D. L., & Halliday, G. M. (2019). Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety. Experimental Dermatology.
Navarrete-Solís, J. et al. (2011). A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Dermatology Research and Practice, 2011.