Dermal Diagnosis™ | ADPA

your dermal diagnosis™ results

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We're thrilled you're taking proactive steps to understand your skin better. Below, you'll find your most recent Dermal Diagnosis™ results. Use this data as a roadmap to achieving healthier skin.

Date	Dermal Diagnosis™	Profile and Treatment Plan

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score	Hydration Score	Pigmentation Score	Inflammation category

Date	Dermal Diagnosis™

DERMAL DIAGNOSIS™ RESULT BREAKDOWN

Aging Score
Hydration Score
Pigmentation Score
Inflammation category

's Dermal Diagnosis™ Profile

Aging . Dry . Pigmentation . Allergy during pregnancy

Navigating the complexities of your ADPA Skin Type during pregnancy, characterized by aging, dryness, pigmentation, and allergy-proneness, is even more challenging when likely dealing with atopic dermatitis. This condition exacerbates your skin’s vulnerabilities, requiring an especially gentle and targeted approach to maintain health and manage symptoms safely during pregnancy.

Pregnancy can alter your skin's natural sebum production, potentially worsening dehydration and weakening an already compromised barrier, which is crucial for protecting against external irritants and allergens. This compromised barrier function is a significant concern in atopic dermatitis, which can intensify dryness and increase susceptibility to environmental triggers.

Additionally, the chronic inflammation characteristic of atopic dermatitis may further affect the activity of melanocytes, exacerbating uneven pigmentation issues. This leads to changes in the skin's appearance and texture, making it feel rough and tight, and lacking the elasticity typically associated with healthy, hydrated skin.

The challenge with managing ADPA skin type in the context of pregnancy and atopic dermatitis lies in its predisposition to severe dryness and an inherently compromised barrier function. It's crucial to select skincare products that are safe for pregnancy, provide deep hydration, and strengthen the skin's barrier without causing further irritation or triggering allergic reactions.

Embracing a comprehensive approach tailored to your specific needs involves using regimens focused on intense moisturization, barrier repair, and soothing anti-inflammatory ingredients. Such a strategy aims to nurture and protect your skin, promoting a more resilient and even-toned complexion. Remember, your skin’s journey is deeply personal, and finding the right balance of care often requires careful experimentation and adjustment. This personalized approach can help effectively manage your conditions, fostering a healthier and more vibrant skin state during and after pregnancy.

benefits

barriers

goals

YOUR SKIN'S MAIN CHARACTERISTICS

Allergy Prone

Pigmentation

Aging Skin

Dehydration

Benefits of your ADPA Pregnancy skin type

resilient skin

structured routine

skincare awareness

Resilience Against Inflammatory Skin Conditions: Despite the complexities of managing multiple skin concerns, your skin may exhibit a natural resilience against inflammatory conditions such as acne and rosacea, due to its dry nature and the careful attention required to manage its sensitivity and allergen exposure.
Structured Skincare Routine: Having a complex skin type means you're likely already in tune with your skin's needs and have a structured skincare routine in place. This disciplined approach is beneficial for addressing each concern systematically, allowing for better management of your skin's overall health.
Heightened Awareness of Ingredients: Being allergy-prone makes you more vigilant about the ingredients in your skincare products. This heightened awareness can lead to more informed choices, reducing the risk of adverse reactions and promoting skin health.

Barriers to your skin health

Pigmentation

Aging skin

Dehydration

Allergy Prone

Compromised Skin Barrier: The combination of aging, dehydration, pigmentation, and allergy-proneness implies that the skin barrier may be compromised, making it less effective at retaining moisture and protecting against external aggressors. This can lead to increased sensitivity and challenges in managing overall skin health.
Hyperpigmentation: ADPA skin has to contend with pigmentation issues. This could include uneven skin tone, dark spots, or melasma, which can be challenging to manage in conjunction with dryness and sensitivity.
Skin Aging: The natural aging process can be more pronounced in ADA Skin Types due to the dry nature of the skin and the potential for allergic reactions that may further stress the skin. Aging in this context is characterized by developing fine lines, wrinkles, and a loss of elasticity and firmness.
Dehydration and Dryness: Your ADPA skin type struggles with maintaining moisture due to an impaired barrier function, leading to dryness and flakiness. This can exacerbate the appearance of aging signs and make the skin more susceptible to irritants.
Allergy prone: Being prone to allergies means your skin may react more sensitively to various external factors, including certain skincare ingredients, environmental allergens, or dietary triggers. This can lead to redness, itching, and irritation, making it crucial to identify and avoid known allergens in your skincare and lifestyle.

your frustrations

Impaired and dehydrated skin barrier.
Visible signs of skin aging.
Rough skin texture.
Sensitive skin that reacts to various stimuli and products.
Skin prone to allergic reactions.
Uneven skin tone with dark spots or patches.

your goals

Restore hydration and moisture.
Strengthen skin barrier.
Smooth skin texture.
Reduce and prevent visible signs of skin aging.
No allergic skin reactions.
Radiant skin with an even skin tone.

Aging . Dry . Pigmentation . Allergy during pregnancy

treatment objectives

Inhibit hyperpigmentation

Inhibit the pathways in the hyperpigmentation process to stop the stimulation, production and transfer of melanin (pigment cells).

Intensive Moisturization

Prioritize deep hydration to improve the skin's intrinsic ability to retain water and encourage the skin's production of natural moisturizing factors (NMFs) to sustain long-term hydration levels.

Skin Barrier Restoration

Repair and strengthen the skin's barrier function and enhance the production of natural barrier components like elastin and collagen to fortify the skin against allergens and environmental stressors.

Enhance Skin Texture

Employ mild resurfacing techniques that encourage collagen remodeling, improving skin resilience and reducing the appearance of fine lines and wrinkles.

Prevent & Repair Skin Aging

Address premature aging with ingredients that support skin renewal and repair DNA damage. Antioxidants can protect against oxidative stress, while peptides and retinoids can stimulate collagen production.

Allergy Management

Implement a skincare regimen that minimizes the risk of allergic reactions with hypoallergenic, fragrance-free, and non-irritating formulations.

include

Anti-inflammatory, anti-microbial and pigmentation-disruptive ingredients.
Broad spectrum sunscreen with antioxidants - preventing premature aging and protecting DNA.
Effective barrier repair agents restore your skin's natural barrier and prevent premature aging.
Hypoallergenic and pigmentation-disruptive ingredients.
Skin-identical medical-grade ingredients that penetrate the skin to activate a biological response.

avoid

Damaging lifestyle habits, e.g., smoking, tanning beds, excessive sun, and sugar consumption.
Toners and foaming cleansers containing soap & sulfates.
Fragrance in skincare products.
Harsh anti-bacterial products that disrupt the skin's natural microbiome.
Irritating plant extracts and essential oils that will trigger adverse reactions.

Aging . Dry . Pigmentation . Allergy during pregnancy

Active Ingredients your skin needs

Azelaic acid

Azelaic acid, a naturally occurring dicarboxylic acid, is an effective ingredient in dermatological treatments, particularly for acne, rosacea, and hyperpigmentation, with antimicrobial and anti-inflammatory properties.

Physiological Effects

Anti-Inflammatory Properties: Azelaic acid reduces inflammation, effectively treating inflammatory skin conditions like acne and rosacea.
Antimicrobial Action: It possesses antimicrobial properties that target acne-causing bacteria (Propionibacterium acnes), helping to reduce acne outbreaks.
Keratolytic Effects: It helps unclog pores and reduce the formation of comedones (black and whiteheads) by normalizing the shedding of skin cells.
Depigmenting Agent: Azelaic acid effectively treats hyperpigmentation disorders, including melasma, as it inhibits tyrosinase, an enzyme involved in melanin production.

Role in Managing Dermatological Conditions

Acne: Azelaic acid inhibits the proliferation of acne-causing bacteria on the skin’s surface, thereby reducing bacterial growth and inflammation. Its antibacterial activity is primarily against Propionibacterium acnes, a key bacterium involved in the development of acne. Furthermore, azelaic acid helps unclog pores and reduce skin cell buildup, effectively treating mild to moderate acne.
Rosacea: Azelaic acid's anti-inflammatory action helps to reduce redness and swelling associated with rosacea. In addition, azelaic acid's ability to reduce keratinization (the process by which skin cells become more fibrous and less flexible) contributes to its effectiveness in this condition.
Pigmentation: Azelaic acid effectively treats melasma and post-inflammatory hyperpigmentation by inhibiting tyrosinase, an enzyme in melanin production. This helps to reduce the formation of excess pigment and can lead to a more even skin tone.

References

Fitton, A., & Goa, K. L. (1991). Azelaic Acid. Drugs.
Gollnick, H., & Schramm, M. (1998). Topical drug treatment in acne. Dermatology.
Passeron, T., et al. (2019). Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a low-dose retinoid. G Ital Dermatol Venereol.
Wolf, J. E., Kerrouche, N., & Arsonnaud, S. (2006). Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. Cutis, 77(4 Suppl), 3-11.
Hollinger, J. C., Angra, K., & Halder, R. M. (2018). Are natural ingredients effective in the management of hyperpigmentation? A systematic review. The Journal of clinical and aesthetic dermatology, 11(2), 28.

Alpha Arbutin

Alpha Arbutin is a derivative of hydroquinone and a biosynthetic active ingredient. Its primary action is inhibiting tyrosinase, a key enzyme involved in the synthesis of melanin, the pigment responsible for skin color. Alpha Arbutin effectively reduces melanin production in the skin by inhibiting tyrosin activity. This gradually lightens hyperpigmented areas, such as age spots, melasma, and scars, resulting in a more even skin tone.

One of the significant advantages of Alpha Arbutin over other skin-lightening agents is its safety profile. Unlike hydroquinone, which has been associated with potential side effects and is restricted in many countries, Alpha Arbutin is considered safe and less irritating to the skin, even at higher concentrations. This makes it a suitable ingredient for all skin types, including sensitive skin.

In addition to its skin-lightening properties, Alpha Arbutin has also shown antioxidant effects, helping to protect the skin from oxidative stress caused by environmental factors like UV radiation and pollution.

Physiological Effects

Melanin Inhibition: Alpha Arbutin works by inhibiting tyrosinase, the enzyme responsible for melanin production in the skin. This action reduces the formation of melanin, leading to a lightening of skin pigmentation.
Even Skin Tone: Regular use of alpha arbutin can lead to a more even skin tone overall, reducing the appearance of age spots and hyperpigmentation.
Reduced Skin Discoloration: It effectively reduces the appearance of dark spots and areas of hyperpigmentation, such as those caused by acne, sun damage, or hormonal changes.
Safer Alternative to Hydroquinone: While structurally similar to hydroquinone, alpha arbutin is a safer option with a lower risk of side effects.

Role in Managing Dermatological Conditions

Hyperpigmentation: Alpha arbutin treats melasma, sun spots, and post-inflammatory hyperpigmentation from acne.
Skin Brightening: Provide a more radiant and uniform skin tone.
Anti-Aging: Reduce the appearance of age-related spots and uneven skin tone.